Carbamates of ergolines and therapeutic compositions therewith

Details Carbamates of ergolines and therapeutic compositions therewith Carbamates of ergolines and therapeutic compositions therewith

1975-08-19

1977-11-08

Randolph, John D.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

424246, 424250, 260268PE, 2602855, 544125, A61K 3140, C07D45706

Patent

active

040576353

ABSTRACT:
Ergoline carbamates are disclosed, which have proven to be effective spasmolytic and vasodilatory drugs. They are derivatives of D-6-methyl-8.beta.-(methanol)-9,10-didehydroergoline (also called lysergol). Three convenient methods for their preparation are also disclosed. The toxicity of these compounds is extremely low.

REFERENCES:
patent: 3236852 (1966-02-01), Bernardi et al.
patent: 3704233 (1972-11-01), Eich et al.
patent: 3944582 (1976-03-01), Ferrari et al.
Chemical Abstracts, vol. 82, abst. no. 140,365r (1975).

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