Carbacyclins, process for the preparation thereof, and use there

Details Carbacyclins, process for the preparation thereof, and use there Carbacyclins, process for the preparation thereof, and use there

1988-01-06

1992-06-23

Gerstl, Robert

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514530, 514573, 514601, 514616, 514729, 548237, 560116, 562498, 564 98, 564152, 568819, C07C17700, A61K 31557

Patent

active

051243431

ABSTRACT:
The invention relates to carbacyclins of general Formula I ##STR1## wherein R.sub.1 is the residue CH.sub.2 OH or ##STR2## with R.sub.2 meaning a hydrogen atom, an alkyl, cycloalkyl, aryl residue, a ##STR3## or heterocyclic residue, or R.sub.1 is the residue ##STR4## with R.sub.3 meaning an alkanoyl or alkanesulfonyl residue of respectively 1-10 carbon atoms or the residue R.sub.2, or

REFERENCES:
patent: 4405468 (1977-08-01), Kurono et al.
patent: 4423067 (1983-12-01), Skubulla
patent: 4692464 (1987-09-01), Skuballa et al.
Prostaglanding; November 1981, vol. 22, No. 5, pp. 809-830.

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