Capture moieties for nucleic acids and uses thereof

Details Capture moieties for nucleic acids and uses thereof Capture moieties for nucleic acids and uses thereof

2011-03-29

2011-03-29

Lu, Frank W (Department: 1634)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S091100, C536S023100, C536S024300, C536S024330, C536S025300

Reexamination Certificate

active

07914989

ABSTRACT:
A unimolecular probe for hybridization to a molecule comprising a target nucleic acid sequence, the probe includes: a first nucleic acid sequence complementary to the target sequence (target-binding sequence); and a second nucleic acid sequence complementary to a portion of the first nucleic acid sequence and capable of hybridization therewith to form a first intramolecular duplex. In use, the target and target-bind sequence hybridize to form a duplex. A probe can be used to detect a molecule containing the target sequence, act as a primer for synthesis or amplification, etc.

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