Capsule shell

Details Capsule shell Capsule shell

1997-02-07

1998-05-26

Hulina, Amy

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Capsules

424452, 424455, 424494, A61K 948

Patent

active

057561230

ABSTRACT:
A capsule shell comprising 79.6-98.7% by weight of a hydroxypropylmethyl cellulose, 0.03-0.5% by weight of carrageenan, and 0.14-3.19% by weight of a potassium ion and/or a calcium is prepared by drying an solution comprising 18-28% by weight of hydroxypropylmethyl cellulose whose 2% aqueous solution has a viscosity of 2.4-5.4 centistokes at 20.degree. C. as a base, 0.01-0.09% by weight of carrageenan as a gelling agent, and 0.05-0.6% by weight of a potassium ion and/or calcium ion as a co-gelling agent. The capsule shell exhibits disintegrating ability equivalent to gelatin shells without degrading that ability even under special conditions containing much calcium ions.

REFERENCES:
patent: 3617588 (1971-11-01), Langman
patent: 4001211 (1977-01-01), Sarkar
patent: 4993137 (1991-02-01), Muto et al.
patent: 5032074 (1991-07-01), Muto et al.
patent: 5264223 (1993-11-01), Yamamoto et al.
patent: 5431917 (1995-07-01), Yamamoto et al.

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