Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Glycoprotein – e.g. – mucins – proteoglycans – etc.
Patent
1986-07-11
1988-04-26
Foelak, Morton
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Glycoprotein, e.g., mucins, proteoglycans, etc.
530350, 530402, 530403, 424 88, 424 92, 536 11, 536123, 514 2, 514 6, C07K 1500, A61K 3902
Patent
active
047405899
ABSTRACT:
Complexes comprising a metal constituent and a bacterial capsular polysaccharide constituent, wherein the polysaccharide contains sialic acid, are useful in the prophylaxis and treatment of bacterial diseases. The polysaccharide is preferably colominic acid or meningoccal group B polysaccharide. Preferred metals are aluminum and ruthenium. The complexes preferably also contain a third constituent of bacterial outer-membrane protein. Some of the complexes, especially when formulated as vaccines, are particularly applicable in the prophylaxis and treatment of cerebrospinal meningits.
REFERENCES:
patent: 4384113 (1983-05-01), Daly
patent: 4490525 (1984-12-01), Hayatsu et al.
Robuste et al., Cien & Ind. Farm 9, 1977, pp. 159-163, (English Translation).
Kedzierska, Chem. Abs., 67, 8845h, (1967).
Liu et al., Chem. Abs., 88, 168255t, (1978).
Zollinger et al., Chem. Abs., 96, 179171p, (1982).
Crescenzi et al., Chem. Abs., 94, 157409d, (1981).
Rendelman, Chems. Abs., 88, 165528h, (1978).
Rendelman, Chem. Abs., 89, 5477m, (1978).
Brown Donald
Burroughs Wellcome Co.
Draper Garnette D.
Foelak Morton
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