Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Patent
1996-07-02
1998-11-03
Scheiner, Laurie
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
424 932, 435 691, 4351723, 4352523, 530826, A01N 6300
Patent
active
058310134
ABSTRACT:
The present invention is directed to a viral capsid polypeptide capable of inhibiting viral packaging, the viral capsid polypeptide consisting of a portion of a viral capsid protein of an RNA virus and including a multimerization domain of the viral capsid protein. The invention further provides an isolated nucleic acid molecule encoding such a viral capsid polypeptide. Expression vectors and host cells comprising the nucleic acid molecules are also provided, as well as a method for inhibiting viral packaging in a host cell by expressing the viral capsid polypeptide. In two preferred embodiments, the RNA virus is the ScVL1 virus or the ScVLa virus of Saccharomyces cerevisiae.
REFERENCES:
patent: 4970168 (1990-11-01), Tumer
patent: 5185253 (1993-02-01), Tumer
patent: 5304730 (1994-04-01), Lawson et al.
Valle, R.P.C. and Wickner, R.B., J. of Virology, 67(5):2764-2771 (1993).
Wickner et al., J. of Virology, 65(1):155-161 (1991).
Park et al., Virology, 218:451-454 (1996).
Yao et al., J. of Virology, 69(3):1917-1919 (1995).
Lindbo, J.A. and Dougherty, W.G., Virology, 189:725-733 (1992).
Lindbo, J.A. and Dougherty, W.G., Molecular Plant Microbe Interat., 5(2):144-153 (1992).
Diamond et al., J. of Virology, 63(9):3983-3990 (Sep. 1989).
Yao, W. and Bruenn, J.A., Virology, 214:215-221 (1995).
Bruenn Jeremy A.
Yao Wensheng
Braman, Esq. Susan J.
Scheiner Laurie
The Research Foundation of State University of New York
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