Capping enzyme of flavivirus and utilization of this protein...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving transferase

Reexamination Certificate

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C435S005000, C435S193000, C435S235100, C530S350000

Reexamination Certificate

active

06949353

ABSTRACT:
This invention concerns an isolated and purified polypeptide capable of acting as a guanylyltransferase and methyltransferase comprising capping enzyme offlavivirus(CEF). The invention also concerns the use of such polypeptide to identify biologically active molecule wich can be used in the treatment or the prevention of diseases resulting fromFlavivirusinfection.

REFERENCES:
patent: 2002/0164348 (2002-11-01), Kirkegaard et al.
Steffens et al (Journal of General Virology 80:2583-2590, 1999).
Raviprakash et al (American Journal of Tropical Medicine and Hygiene 58:90-95, 1998).
Koonin (Journal of General Virology 74:733-740, 1993).
Leyssen et al (Clinical Microbiology Reviews 13:67-82, 2000).

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