Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-06-20
2006-06-20
Wilson, James O. (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C544S407000, C544S212000, C544S277000, C514S245000
Reexamination Certificate
active
07064129
ABSTRACT:
Compounds are provided which are represented by the formula:where the structural variables are defined herein. The present invention also includes a variety of methods of treatment using these inventive sodium channel blockers.
REFERENCES:
patent: 4894376 (1990-01-01), Morad et al.
patent: 6858615 (2005-02-01), Johnson
patent: 2004/0162296 (2004-08-01), Johnson
patent: 2004/0195160 (2004-10-01), Max et al.
patent: 2004/0198744 (2004-10-01), Johnson
patent: 2004/0198745 (2004-10-01), Johnson
patent: 2004/0198746 (2004-10-01), Johnson
patent: 2004/0198747 (2004-10-01), Johnson
patent: 2004/0198748 (2004-10-01), Johnson
patent: 2004/0198749 (2004-10-01), Johnson
patent: 2004/0199456 (2004-10-01), Flint et al.
patent: 2004/0204424 (2004-10-01), Johnson
patent: 2004/0204425 (2004-10-01), Johnson
patent: 1.525.670 (1968-04-01), None
patent: 1.525.671 (1968-04-01), None
Kellerman, D. “P2Y2 Receptor Agonists” CHEST, vol. 121(5), pp. 201S-205S (May, 2002 Supplement).
Cragoe, Jr., et al., Journal of Medicinal Chemistry, Jan. 1967, vol. 10, No. 1, pp. 66-75, “Pyrazine Diuretics. II. N-Amidino-3-amino-5-substituted 6-Halopyrazinecarboxamides”.
Kleyman, et al., American Journal of Physiology, 1991, vol. 260, Pt. 1, pp. C271-C276, “Distinct Epitopes on Amiloride. II Variably Restricted Epitopes Defined by Monoclonal Anti-Amiloride Antibodies”.
Cocks, et al., British Journal of Pharmacology, 1988, vol. 95, pp. 67-76, “Amiloride Analogues Cause Endothelium-Dependent Relaxation in the Canine Coronary Artery in Vitro; Possible Role of Na+/Ca2+Exchange”.
Johnson Michael R.
Molino Bruce
Sargent Bruce
Zhang Jianzhong
Parion Sciences, Inc.
Tucker Zachary C.
Wilson James O.
LandOfFree
Capped pyrazinoylguanidine sodium channel blockers does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Capped pyrazinoylguanidine sodium channel blockers, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Capped pyrazinoylguanidine sodium channel blockers will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3628798