Capillary tube immunoassay

Details Capillary tube immunoassay Capillary tube immunoassay

1984-12-19

1987-09-01

Warden, Robert J.

Chemistry: analytical and immunological testing

Involving diffusion or migration of antigen or antibody

436515, 436518, 436524, 436527, 422 56, G01N 33558, G01N 33557, G01N 33543, G01N 33551

Patent

active

046909079

ABSTRACT:
A component of a sample may be detected or quantitatively measured by an immunoreaction, namely causing a target substance-immunoreactive reagent labelled with a marker-reaction product and/or any remaining, unreacted, immunoreactive reagent to move while making use of capillarity, causing the reaction product or any remaining, unreacted, immunoreactive reagent to combine with a substance packed in a capillary tube, and is immobilized on a carrier and adapted to uptake labelled substance so as to immobilize the reaction product or any remaining, unreacted, immunoreactive reagent, and measuring the amount of the thus-immobilized labelled substance. Since reagents are all filled in the capillary tube, there is no such troublesome that the reagents have to be prepared and/or any extra reagents have to be discarded upon conducting the measurement. The immunoassay may be carried out at bed side in hospitals. An extremely small amount of the sample may be sufficient for its measurement. After the measurement, the capillary tube may be stored as is or may be thrown away with ease.

REFERENCES:
patent: 4116638 (1978-09-01), Kenoff
patent: 4235601 (1980-11-01), Deutsch et al.
patent: 4305924 (1981-12-01), Piasio et al.
patent: 4447546 (1984-05-01), Hirschfeld

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