Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Reexamination Certificate
2006-05-09
2006-05-09
Wilson, James O. (Department: 1623)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
C514S059000, C514S060000, C514S833000, C424S094400, C435S018000
Reexamination Certificate
active
07041655
ABSTRACT:
In accordance with the invention there is provided a method of treating a human subject to prevent leakage of serum proteins from capillary endothelial junctions during a period of increased capillary permeability. The invention also provides a method for preventing the harmful effects of free radicals on cellular membranes and other organelles. The method comprises administering to a subject an effective amount of a composition comprising at least one polysaccharide selected from the group consisting of hydroxyethyl starch and dextran of varying molecular sizes and at least one member of the group consisting of superoxide dismutase, glutathione peroxidase, catalase, hydroxyethyl rutoside, cyclic adenosine monophosphate and vitamin C. The compositions contain the macromolecules in a molecular size and concentration to effectively stabilize the capillary membrane. The stabilization effect is accomplished by a biophysical/biochemical process due to the adhesiveness and configuration of the macromolecules and because of their size. The treatment is benign as the macromolecules and antioxidants and non-toxic and biodegradable.
REFERENCES:
patent: 4994444 (1991-02-01), Zikria
Weiss, Stephen J. J. Biol. Chem. 255:20, 9912-9917, 1980.
Gerdin. et al. Chem. Abstr. No. 99:47701p, p. 34, 1983, Int. J. Microcirc. Clin. Exp. 2(1):39-46, 1983.
Munkres et al. EMBASE Abstr. No. 8418469, Age, 7(2): 30-35, 1984.
Zikria Bashir
Zikria Jemal D.
Owens Howard V.
Sommer Evelyn M.
Wilson James O.
LandOfFree
Capillary membrane stabilization and reduction of tissue... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Capillary membrane stabilization and reduction of tissue..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Capillary membrane stabilization and reduction of tissue... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3530833