Capillary flowcell for multiple wavelength detection

Details Capillary flowcell for multiple wavelength detection Capillary flowcell for multiple wavelength detection

1994-04-15

1995-07-18

McGraw, Vincent P.

Optics: measuring and testing

Sample, specimen, or standard holder or support

356246, 356440, G01N 2105

Patent

active

054346649

ABSTRACT:
A capillary flowcell of this invention comprises a holding means including an optical axis, the optical axis being defined by, in sequential order, (a) a first (entrance) aperture, (b) a first lens, (c) a capillary tube having its long axis centered across the optical axis, and (d) a second lens. The first lens focuses electromagnetic radiation from the entrance aperture passes through the inner diameter of the capillary tube, thus maximizing the signal generated by the analyte within the capillary tube. The second lens focuses electromagnetic radiation which has passed through the capillary tube. Methods and apparatus pertaining to the flowcell are given.

REFERENCES:
patent: 4991958 (1991-02-01), Garner
patent: 5037199 (1991-08-01), Hlousek
Albin et al "Fluorescence Detection in Capillary Electrophoresis: Evaluation of Derivatizing Reagents & Techniques"; Analytical Chemistry, vol. 63 #5 Mar. 1, 1991 pp. 417-422.
Kobayashi et al; "Photodiode array Detection in High-Performance Capillary Electrophoresis", J. Chrom. 480(1989; pp. 179-184).
Moring et al., "Analytical Aspects of an Automated Capillary Electrophoresis System", LC:GC 8(1):34-46 (1990).
Sepaniak et al., "Instrumental Developments in Micellar Electrokinetic Capillary Chromatography", J. Chrom. 480 (1989):185-196.

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