Capillary flow device and method for measuring activated partial

Details Capillary flow device and method for measuring activated partial Capillary flow device and method for measuring activated partial

1989-04-20

1991-08-13

Lacey, David L.

Chemistry: analytical and immunological testing

Clotting or clotting factor level tests

435 13, 435810, 422 57, 422 58, 422 73, 422 81, G01N 3386

Patent

active

050396170

ABSTRACT:
Methods and devices are provided for carrying out activated partial thromboplastin time (APTT) analysis on a whole blood sample to which no anticoagulant has been added by applying the sample to a capillary track contained in a housing, wherein the capillary track comprises sample entry and venting ports, at least one capillary track connecting the entry and venting ports, and reagents capable of initiating an APTT analysis, wherein clotting time is measured by the cessation of blood flow in the capillary track.

REFERENCES:
patent: 4672030 (1987-06-01), Witt
patent: 4755461 (1988-07-01), Lawson et al.
patent: 4756884 (1988-07-01), Hillman et al.
patent: 4761381 (1988-08-01), Blatt et al.
patent: 4849340 (1989-07-01), Oberhardt
Tans et al., "Properties of Sulfatides in Factor-XII-Dependent Contact Activation", Blood (1982), 59:69-75, No. 1.
Thomson, "The activated partial thromboplastin time", in Blood Coagulation and Haemostatis, a practical guide [Chapter 7], Churchill Livingston, Inc., New York (1985).

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