Capillary electrophoresis using a conductive capillary tube

Details Capillary electrophoresis using a conductive capillary tube Capillary electrophoresis using a conductive capillary tube

1995-07-13

1997-05-20

Gorgos, Kathryn L.

Chemistry: electrical and wave energy

Apparatus

Electrophoretic or electro-osmotic apparatus

204433, 204601, 204451, G01N 2726

Patent

active

056309252

ABSTRACT:
An electrophoretic system employing a capillary with at least one end having an electrically conductive coating or layer directly thereon. In order to introduce a plug of sample from a small amount of the sample in a vial, the conductive tip is submersed into the small amount of sample and an electric field is applied at the end by applying the high voltage to the tip in order to electrokinetically inject a plug of the sample. The conductive tip may also be used as a terminal for completing the circuit for applying the high voltage across the capillary column for electrophoresis. The separated components may be collected on a surface or small amount of buffer to reduce sample dilution or mixing of one sample component with a different sample component from the electrophoretic process.

REFERENCES:
patent: 4842701 (1989-06-01), Smith et al.
"Postcolumn Radionuclide Detection of Low-Energy .beta. Emitters in Capillary Electrophoresis," by Tracht et al., Anal. Chem., 1994, 66, 2382-2389.

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