Capillary electrophoresis systems and additives

Chemistry: electrical and wave energy – Processes and products – Electrophoresis or electro-osmosis processes and electrolyte...

Reexamination Certificate

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C204S468000

Reexamination Certificate

active

10052931

ABSTRACT:
Capillary electrophoresis systems, reagents, and processes for analyzing a sample which includes at least one protein constituent are disclosed. The processes involve introducing the sample into a capillary tube containing a buffer system, wherein said buffer system includes at least one additive having a hydrophobic interaction with said at least one protein constituent and providing said at least one protein constituent with at least one negative charge thereby modifying the electrophoretic mobility.

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Lauer et al, “Capillary Zone Electrophoresis of Proteins in Untreated Fused Silica Tubing,” Anal. Chem., vol. 58, pp. 166-170, (1986).

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