Capillary electrophoresis system

Chemistry: electrical and wave energy – Apparatus – Electrophoretic or electro-osmotic apparatus

Reexamination Certificate

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C204S603000, C204S605000

Reexamination Certificate

active

10609554

ABSTRACT:
A capillary electrophoresis system includes a plurality of capillaries arranged in parallel on a vertical plane at an identical distance from each other, each of which has a sample injection end immersed in a cathode buffer23and pointed downward vertically to facilitate connection between the cathode buffer23and a sample solution. The sample elution end is connected via a pump block11and a connection tube3to an anode buffer24.The height is made identical between the liquid levels for buffers23and24to prevent movement of the separation medium in the capillaries. The sample introduced from the sample injection end20moves upward vertically via electrophoresis to the sample elution end in the capillary and is passed through and detected at the fluorescence detection position19. The effective separation length is thus decreased to 10 cm or less to attain high throughput.

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JPO computer translation of JP 2000-227413 A.
Howard Drossman, John A. Luckey, Anthony J. Kostichka, Jonathjan D'Cunha and Lloyd M. Smith, “High-Speed Separations of DNA Sequencing Reactions by Capillary Electrophoresis”, Anal. Chem. 1990, vol. 62, pp. 900-903.
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