Capillary electrophoresis flow control system

Details Capillary electrophoresis flow control system Capillary electrophoresis flow control system

1993-01-19

1996-01-09

Niebling, John

Chemistry: electrical and wave energy

Apparatus

Coating, forming or etching by sputtering

2041801, 2041828, 356344, C25B 900

Patent

active

054826080

ABSTRACT:
A system for controlling the bulk flow rate in capillary electrophoresis employs pressure to increase velocity without unacceptably increasing plate height. Thus, the system controls bulk flow over a range of velocities, independent of the chemistry of the system. Additionally, the use of pressure under certain conditions may decrease plate height and improve resolution.

REFERENCES:
patent: 3705845 (1972-12-01), Everaerts
patent: 3869365 (1975-03-01), Sunden
patent: 4906344 (1990-03-01), Hjerten
patent: 5061361 (1991-11-01), Gordon
patent: 5302264 (1994-04-01), Welch et al.
Ravindra Datta, Veerabhadra R. Kota Marthi, "Electrokinetic Dispersion In Capillary Electrophoresis," Jun. 1990, vol. 36, No. 6, pp. 916-926.
CA 113 (23): 207828y, Single-stranded RNA molecular weight and shape determination by differential pressure capillary viscometry, sedimentation velocity, and gel electrophoresis.
CA 113 (26): 238658x, High Pressure and Super-critical Capillary Electrophoresis.
Everaerts et al., Journal of Chromotography, 60:397-405 (1971).
Everaerts et al., Journal of Chromotography, 19:262-268 (1970).

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