Chemistry: electrical and wave energy – Apparatus – Electrophoretic or electro-osmotic apparatus
Patent
1998-02-20
2000-08-15
Warden, Sr., Robert J.
Chemistry: electrical and wave energy
Apparatus
Electrophoretic or electro-osmotic apparatus
204452, 356344, G01N 27447, G01N 2700
Patent
active
06103083&
ABSTRACT:
The present invention relates to an electrophoresis apparatus having a plurality of capillaries arranged in a plane such that a curving contour is formed by the intersection points of each of the capillaries with the plane. The apparatus may be used to determine the sequence of nucleic acids. The present invention also relates to methods of using the electrophoresis apparatus and methods of making the electrophoresis apparatus.
REFERENCES:
patent: 3980891 (1976-09-01), Slaker
patent: 4374723 (1983-02-01), Vesterberg
patent: 4375401 (1983-03-01), Catsimpoolas
patent: 4675095 (1987-06-01), Kambara et al.
patent: 4811218 (1989-03-01), Hunkapiller et al.
patent: 4832815 (1989-05-01), Kambara et al.
patent: 4879012 (1989-11-01), Kambara et al.
patent: 4930893 (1990-06-01), Manian
patent: 5062294 (1991-11-01), Iwata
patent: 5091652 (1992-02-01), Mathies et al.
patent: 5192412 (1993-03-01), Kambara et al.
patent: 5274240 (1993-12-01), Mathies et al.
patent: 5324401 (1994-06-01), Yeung et al.
patent: 5340747 (1994-08-01), Eden
patent: 5413686 (1995-05-01), Klein et al.
patent: 5439578 (1995-08-01), Dovichi et al.
patent: 5483075 (1996-01-01), Smith et al.
patent: 5498324 (1996-03-01), Yeung et al.
patent: 5560811 (1996-10-01), Briggs et al.
patent: 5597468 (1997-01-01), Lauer et al.
patent: 5730850 (1998-03-01), Kambara et al.
patent: 5833827 (1998-11-01), Anazawa et al.
patent: 5885430 (1999-03-01), Keman et al.
Clark, et al., "High-Speed Parallel Separation of DNA Restriction Fragments Using Capillary Array Electrophoresis.sup.1 ", Analytical Biochemistry, 215 :163-170 (1993).
Takahashi, et al., Multiple Sheath-Flow Gel Capillary-Array Electrophoresis for Multicolor Fluorescent DNA Detection, Anal. Chem., 66(7):1021-1026 (1994).
Ueno, et al., "Simultaneous Monitoring of DNA Fragments Separated by Electrophoresis in a Multiplexed Array of 100 Capillaries", Anal. Chem., 66(9):1424-1431 (1994).
Xiaohua C. Huang et al., Capillary Array Electrophoresis Using Laser-Excited Confocal Fluorescence Detection. American Chemical Society 1992, 64, 967-971.
M.A. Quesada, et al., High -Sensitivity DNA Detection With A Laser-Excited Confocal Fluorescence Gel Scanner. BioTechniques, 1991, vol. 10, No. 5, 616-625.
Harold Swerdlow, et al., Three DNA Sequencing Methods of Using Capillary Gel Electrophoresis and Laser-Induced Fluorescence, American Chemical Society, 1991, 63, 2835-2841.
Brevnov Maxim
Merenkova Irena N.
Aldag Andrew
Tetragen
Warden, Sr. Robert J.
LandOfFree
Capillary electrophoresis apparatus and method does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Capillary electrophoresis apparatus and method, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Capillary electrophoresis apparatus and method will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2002790