Chemistry: electrical and wave energy – Apparatus – Electrophoretic or electro-osmotic apparatus
Patent
1997-04-22
1999-08-17
Warden, Robert
Chemistry: electrical and wave energy
Apparatus
Electrophoretic or electro-osmotic apparatus
356344, G01N 2726
Patent
active
059389087
ABSTRACT:
A capillary electrophoresis system comprising a plurality of capillaries filled with a migration medium in which samples to which fluorephore labels are added migrate, a light source providing an excitation light exciting the fluorephore labels, a photo detector detecting a fluorescence radiated from the fluorephore labels, and light focusing means placed between the plurality of capillaries to which the excitation light is irradiated. The parts of the plurality of capillaries to which the excitation light is irradiated and the light focusing means are arranged in a plane shape. The excitation light is irradiated through the plurality of capillaries and the light focusing means, the capillaries and light focusing means alternatively placed in the parts where an excitation light is irradiated. The light focusing means consisting of cylindrical rod lenses. The axis of the cylindrical rod lenses is placed substantially parallel with the capillaries, which can detect the fluorescence from samples by irradiating a plurality of capillaries substantially at the same time in a batch without mechanical scanning of a plurality of capillaries or without optical scanning of a light beam, providing a highly sensitive detection of samples.
REFERENCES:
patent: 5529679 (1996-06-01), Takahasi et al.
patent: 5567294 (1996-10-01), Dovichi et al.
patent: 5582705 (1996-12-01), Yeung et al.
Page VI/460 of "Polymer Handbook, 3rd Ed.", ed. Brandrup et al., John Wiley & Sons, 1989 month unknown.
Kambara et al. ("Multiple-sheatflow capillary array DNA analyser", Nature, 361(11), 565-566), Feb. 1993.
Huang et al. ("Capillary Array Electrophoresis Using Laser-Excited Confocal Fluorescence Detection", Anal. Chem. 64(8), 967-9720, Apr. 1992.
Takahashi et al. (Multiple Sheath-Flow Gel Capillary-Array Electrophoresis for Multicolor Fluorescent DNA Detection, Anal. Chem., 66(7), 1021-1-26), Apr. 1994.
Anazawa Takashi
Imai Kazumichi
Kambara Hideki
Nasu Hisanori
Takahashi Satoshi
Hitachi , Ltd.
Hitachi Software Engineering Co. Ltd.
Noguerola Alex
Warden Robert
LandOfFree
Capillary array electrophoresis system does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Capillary array electrophoresis system, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Capillary array electrophoresis system will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-312087