Cannabinoids

Details Cannabinoids Cannabinoids

2007-10-23

2007-10-23

Richter, Johann (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Oxygen containing

Reexamination Certificate

active

10512468

ABSTRACT:
Compounds of the formula: wherein R, R1 and R4 are defined in the specification, and pharmaceutically acceptable salts, esters and tautomers thereof, having activity at peripheral cannabinoid receptors, commonly designated the CB2 receptor class. The compounds are useful for therapy, especially in the treatment of pain, inflammation and autoimmune disease.

REFERENCES:
patent: 4092344 (1978-05-01), Matsumoto
patent: 4102902 (1978-07-01), Archer et al.
patent: 4282248 (1981-08-01), Mechoulam et al.
patent: 4707559 (1987-11-01), Mechoulam et al.
patent: 4758597 (1988-07-01), Martin et al.
patent: 5434295 (1995-07-01), Mechoulam et al.
patent: 6274635 (2001-08-01), Travis
patent: 6563009 (2003-05-01), Kunos et al.
patent: 6630507 (2003-10-01), Hampson et al.
patent: WO 01/28329 (2001-04-01), None
patent: WO 01/95899 (2001-12-01), None
Wiley et al (The Journal of Pharmacology and Experimental Therapeutics Jan. 22, 2002, vol. 301, No. 2. pp. 679-689).
Gareau et al (Bioorganic & Medicinal etters, 1996, vol. 6, No. 2, pp. 189-194).
Drake, David J., et al; “Classical/Nonclassical Hybrid Cannabinoids: Southern Aliphatic Chain-Functionalized C-6β Methyl, Ethyl, and Propyl Analogues”;J. Med. Chem.; vol. 41, pp. 3596-3608 (1998) XP-002217966.
Gareau, Y., et al; “Structure Activity Relationships of Tetrahydrocannabinol Analogues on Human Cannabinoid Receptors”;Bioorganic&Medicinal Chemistry Letters; vol. 6, No. 2; pp. 189-194 (1996) XP-004135106.
Baek, Seung-Hwa; “Boron Trifluoride Etherate on Alimina—A Modified Lewis Acid Reagent. An Improved Synthesis of Cannabidiol”;Tetrahedron Letters; vol. 26, No. 8; p. 1083-1086 (1985) XP-001095309.
Baek, Seung-Hwa; “Boron Trifluoride Etherate on Alumina-A Modified Lewis Acid Reagent (VI). Synthesis of 2′-(1-Acetoxymethyl-1-cyclohexen-3-yl)-5′-alkylresorcinol Diacetate Derivatives”;Bull. Korean Chem. Soc.; vol. 15, No. 6; pp. 507-508 (1994) XP-002222551.
Chemical Abstracts Service, Columbus, OH; Baek, Seung-Hwa; “Simplified Cannabidiols. Part 1. Boron trifluoride-diethyl ether on alumina: a modified Lewis acid reagent. Friedel-Crafts alkylation of 5-alkylresorcinols with cyclic allylic alcohols”;J. Chem. Research; pp. 2549-2561 (1994) XP-002222552.

Affiliated with

Also associated with

Rating

Cannabinoids does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Cannabinoids, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cannabinoids will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3847028