Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-03-24
1997-02-25
Ivy, C. Warren
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546108, A61K 31445, C07D22112
Patent
active
056059060
ABSTRACT:
Disclosed are novel cannabinoid (CB2) receptor agonists, their compositions, and the methods of their preparation. The compounds are useful for lowering ocular intra ocular pressure, treating glaucoma, useful as antiinflammatory, immunosuppressive, analgesics agents, and as agents for treatment and prevention of emesis and nausea because of the activity on the cannabinoid receptor.
REFERENCES:
patent: 4228169 (1980-10-01), Johnson et al.
patent: 4260764 (1981-04-01), Johnson
patent: 4309545 (1982-01-01), Johnson
Gogte V N, Salawa, M A, Tilak (1970) Tetrahedron 26, 173-181.
William A. Devane et al., Molecular Pharma, 34, pp. 605-613 (1988).
Sean Munro et al., Nature, 365, pp.61-65 (1993).
Elizabeth A. Frey et al., Eu. J Pharma, 244, pp. 239-250 (1993).
William L. Dewey, Pharma Reviews, 38:2, pp. 151-178 (1986).
John F. Hoops et al., J Org Chem, 33:7, pp. 2995-2996 (1968).
Catherine M. Gerard et al., Biochem J, 279, pp. 129-134, (1991).
W. D. M. Paton, Annual Review Pharma., 15, pp. 191-220 (1975).
H. F. Hardman et al., Proc West Pharma Soc, 14, pp. 14-20 (1971).
William A. Devane et al., J Med Chem, 35:11, pp. 2065-2069 (1992).
Beil, Psychomimeti Drugs, Efron, Raven Press, NY p. 336 (1970).
Ayler Sylvia A.
Daniel Mark R.
Huang Evelyn
Ivy C. Warren
Merck Frosst Canada Inc.
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