Canisters containing aerosol formulations containing P134a and f

Details Canisters containing aerosol formulations containing P134a and f Canisters containing aerosol formulations containing P134a and f

1995-05-19

1997-10-07

Bawa, Raj

Drug, bio-affecting and body treating compositions

Effervescent or pressurized fluid containing

Organic pressurized fluid

424 46, 222635, A61K 912

Patent

active

056744722

ABSTRACT:
The present invention relates to canisters suitable for delivering a pharmaceutical aerosol formulation which comprises a container capable of withstanding the vapor pressure of the propellant used, which container is closed with a metering valve and contains a pharmaceutical aerosol formulation consisting essentially of a particulate medicament which is fluticasone propionate or a physiologically acceptable solvate thereof and 1,1,1,2-tetrafluoroethane as propellant, which formulation contains less than 0.0001% w/w surfactant based on the weight of the medicament, the particulate medicament being present in an amount from 0.005% to 5% w/w relative to the total weight of the formulation and having a particle size of less than 100 microns. A further particulate medicament may also be present in the pharmaceutical aerosol formulation.

REFERENCES:
patent: 2868691 (1959-01-01), Porush et al.
patent: 2885427 (1959-05-01), Rob et al.
patent: 3014844 (1961-12-01), Thiel et al.
patent: 3219533 (1965-11-01), Mullins
patent: 3320125 (1967-05-01), Grim
patent: 3809294 (1974-05-01), Torgeson
patent: 3897779 (1975-08-01), Hansen
patent: 4044126 (1977-08-01), Cook et al.
patent: 4174295 (1979-11-01), Bergigia et al.
patent: 4347236 (1982-08-01), Tanskanen
patent: 4405598 (1983-09-01), Brown
patent: 4814161 (1989-03-01), Jinks et al.
patent: 5118494 (1992-06-01), Schultz et al.
patent: 5126123 (1992-06-01), Jonson
patent: 5182097 (1993-01-01), Byron et al.
patent: 5190029 (1993-03-01), Byron et al.
patent: 5202110 (1993-04-01), Dalby et al.
patent: 5225183 (1993-07-01), Purewal et al.
patent: 5230889 (1993-07-01), Evans
Gennaro, A.R. (1985). Remington's Pharmaceutical Sciences (17th ed.). Mack Pub. Co., pp. 1670-1677.
Oberholz, Frankfurter, Allgemeine Zeitung, 1989, vol. 25, No. 207, p. 7.
Dalby et al., Pharmaceutical Technology, 1990, vol. 14, No. 3, pp. 28-33.
Arnzacort.TM. Carton, William H. Rorer, Inc., Fort Washington, Pennsylvania, USA 19034, 1986.
Pharmaceutical Journal, 1990, vol. 245, pp. 428-429.
The Theory and Practice of Industrial Pharmacy, 2nd Ed., 1978 (Philadelphia, PA: Lee and Febiger), pp. 270 and 276-278.
Handbook of Aerosol Technology, 2nd Edition, 1979 (New York, New York: Van Nostrand Reinhold Company), pp. 30, 32, 33, 166, 167, 232, 233.
U.S. Senate Hearings, 12-14 May 1987, 343-347, 437 (U.S. Government Printing Office, Washington, D.C., 1987), CIS:1987-S321-26.
Hagers Handbook of Pharmaceutical Practice, 1971, pp. 342-354 (Berlin: Springer-Verlag).

Affiliated with

Also associated with

Rating

Canisters containing aerosol formulations containing P134a and f does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Canisters containing aerosol formulations containing P134a and f, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Canisters containing aerosol formulations containing P134a and f will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2354362