Canine herpesvirus based recombinant live vaccine, in particular

Details Canine herpesvirus based recombinant live vaccine, in particular Canine herpesvirus based recombinant live vaccine, in particular

1998-12-16

2000-12-12

Salimi, Ali

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant virus encoding one or more heterologous proteins...

4242291, 4247041, 4242131, 4353201, 536 2372, A61K 3912, A61K 3927, A61K 39175, C12N 1500

Patent

active

061594776

ABSTRACT:
Disclosed and claimed is a recombinant canine herepes virus (CHV). The recombinant CHV includes and expresses at least one heterologous nucleotide sequence encoding an antigen. The antigen can be canine distemper virus HA, canine distemper virus F, rabies virus G, canine parvovirus VP2, parainfluenza virus type 2 HA, parainfluenza virus type 2 F, Borrelia burgdorferi OspA, or Borrelia burgdorferi OspB. The at least one heterologous nucleotide sequence can be in at least one insertion site selected from the group consisting of ORF3 (SEQ ID NO:4), ORF5 (SEQ ID NO:5), the thymidine kinase gene, and the intergenic region corresponding to genes coding for the large subunit and the small subunit. Immunological or vaccine compositions as well as methods for inducing an immunological response are also disclosed and claimed.

REFERENCES:
patent: 4213965 (1980-07-01), Carmichael
patent: 5356622 (1994-10-01), Heath et al.
patent: 5399485 (1995-03-01), Regnery et al.
patent: 5418137 (1995-05-01), Yamanaka et al.
patent: 5681724 (1997-10-01), Tripp et al.
patent: 5707817 (1998-01-01), Wisnewski et al.
patent: 5753235 (1998-05-01), Haanes et al.
patent: 5789194 (1998-08-01), Tripp et al.
patent: 5795768 (1998-08-01), Tripp et al.
patent: 5804197 (1998-09-01), Haanes et al.
U.S. Ser. No. 08/401,509 (no patent publication).
U.S. Ser. No. 08/473,034 (no patent publication).
U.S. Ser. No. 08/482,304 (no patent publication).
U.S. Ser. No. 08/485,434 (no patent publication).
K.J.. Limbach, et al, "Nucleotide sequence of the genes encoding the canine herpesvirus gB, gC and gD homologues", Journal of General Virology, vol. 75, (Aug. 1994) pp. 2029-2039.
M. Redmond, et al, "Gene organization in the UL region and inverted repeats of the canine Herpesvirus genome", Journal of General Virology, (Jan. 1996) 77 (PT 1), pp. 37-48.
M. Redmond, "Sequence of the canine herpesvirus thymidine kinase gene: taxon-preferred amino acid residues in the alphaherpesviral thymidine kinases", Viirus Res. (1995), 39(2-3), pp. 341-354.

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