Canine hepatocyte growth factor

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S325000, C435S320100, C435S252300, C530S399000, C536S023500, C536S024310

Reexamination Certificate

active

07129064

ABSTRACT:
A canine hepatocyte growth factor gene and a 15 base pairs-deleted gene thereof encode a protein having an amino acid sequence shown in SEQ ID NO: 2 or 4 and a protein having an amino acid sequence comprising a deletion, substitution or addition of one or several amino acids and having a canine hepatocyte growth factor activity. The canine hepatocyte growth factor and the 5 amino acids-deleted canine hepatocyte growth factor are useful for the treatment of liver diseases, kidney diseases, lung diseases, digestive diseases, cardiocirculatory diseases or cranial nerve diseases.

REFERENCES:
patent: 5342831 (1994-08-01), Nakamura et al.
patent: 5547856 (1996-08-01), Godowski et al.
patent: 0 412 557 (1991-02-01), None
patent: 0 461 560 (1991-12-01), None
patent: 1291358 (2003-03-01), None
patent: 03-255096 (1991-11-01), None
Skolnick et al. From genes to protein structure and function: novel applications of computational approaches in the genomic era. Trends in Biotech 18(1): 34-39, 2000.
Bork, A. Powers and pitfalls in sequence analysis: the 70% hurdle. Genome Res 10: 398-400, 2000.
Doerks et al. Protein annotation: detective work for function prediction. Trends in Genetics 14(6): 248-250, 1998.
Smith et al. The challenges of genome sequence annotation or “The devil is in the details”. Nature Biotech 15: 1222-1223, 1997.
Brenner, S.E. Errors in genome function. Trends in Genetics 15(4): 132-133, 1999.
Bork et al. Go hunting in sequence databases but watch out for the traps. Trends in Genetics. 12(10): 425-427, 1996.
Wells, J.A. Additivity of mutational effects in proteins. Biochemistry 29 (37): 8509-8517, 1990.
Ngo et al. Computational complexity, protein structure prediction, and the Levinthal paradox. The Protein Folding Problem and Tertiary Structure Prediction, pp. 492-495, 1994.
Kaufman et al. Blood 94: 3178-3184, 1999.
Wang et al. Rapid analysis of gene expression (RAGE) facilitates universal expression profiling. Nucleic Acids Res 27(23): 4609-4618, 1999.
Phillips, A., The challenge of gene therapy and DNA delivery. J Pharm Pharmacology 53: 1169-1174, 2001.
Miyake et al. Canine hepatocyte growth factor: molecular cloning and characterization of the recombinant protein. Vet Immunol Immunopath 95: 135-143, 2003.
Masato Sasaki, et al. “Identification of Mouse Mammary Fibroblast-Derived Mammary Growth Factor as Hepatocyte Growth Factor”, Biochemical and Biophysical Research Communications, Mar. 1994, vol. 199, No. 2, pp. 772-779.
Youhua Liu, et al., “Molecular cloning and characterization of cDNA encoding mouse hepatocyte growth factor”, Biochemica et Biophysica Acta, 1993, vol. 1216, pp. 299-303.
Kosuke Tashiro, et al., “Deduced primary structure of rat hepatocyte growth factor and expression of the mRNA in rat tissues”, Proc. Natl. Acad Sci., U.S.A., Apr. 1990, vol. 87, pp. 3200-3204.
Al Okajima, et al., “Primary structure of rat hepatocyte growth factor and induction of its mRNA during liver regeneration following hepatic injury”, Eur. J. Biochem., 1990, vol. 193, pp. 375-381.
Keiji Miyazawa, et al., “Molecular Cloning and Sequence Analysis of cDNA for Human Hepatocyte Growth Factor”, Biochemical and Biophysical Research Communications, Sep. 1989, vol. 163, No. 2, pp. 967-973.
Database WPI, Section Ch, Week 199119, Derwent Publications Ltd., London, GB, class B04, AN 1991-045716, XP002348456 & JP 03 072883, Mar. 28, 1991, abstract only.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Canine hepatocyte growth factor does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Canine hepatocyte growth factor, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Canine hepatocyte growth factor will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3712788

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.