Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase
Reexamination Certificate
2006-11-28
2006-11-28
Prouty, Rebecca E. (Department: 1652)
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Hydrolase
C435S018000, C435S320100, C435S069100, C435S252300, C435S325000, C530S350000, C424S094600, C536S023100, C536S023200, C536S023500
Reexamination Certificate
active
07141404
ABSTRACT:
A new cytosine deaminase gene and protein fromCandida kefyrare provided. This protein has increased ability to convert the 5-fluorocytosine prodrug to its toxic form when compared against theE. colienzyme.
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Delaney Amy M.
Laquerre Sylvie
Omer Charles A.
Shen Yuqiao
Onyx Pharmaceuticals Inc.
Prouty Rebecca E.
Ramirez Delia M.
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