Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving viable micro-organism
Patent
1983-11-25
1987-06-02
Nucker, Christine M.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving viable micro-organism
435 68, 435173, 435182, C12Q 102, C12P 2100, C12N 1300, C12N 1104
Patent
active
046703861
ABSTRACT:
The present invention provides strongly antigenic tumor-specific substances (also cellular material containing said strongly antigenic tumor-specific substances) prepared by radiofrequency or microwave electromagnetic radiation, acting on cancer tissue or cancer cells of known pathohistologic character. Said substances and also cellular material containing said substances are characterized by such sensitizing antigenic qualities that when they are contacted with a composition of naturally cancer-sensitized lymphocytes taken from a host having pathohistologically related cancer, then said lymphocytes produce and exude lymphokine.
The invention further provides diagnostic tests for cancer and compositions which contain or utilize said strongly-antigenic cancer-specific substances.
REFERENCES:
Svit et al., Cancer Research, vol. 37 (1977), 3836-7.
Hamblin et al., Chem. Abstracts, vol. 89 (1978) 17136j.
Thompson et al., Chem. Abstracts, vol. 89 (1978) 144781v.
McCollester et al., Chem. Abstracts, vol. 93 (1980) 19533t.
Li et al., Nature, 267 (May 12, 1977) 163-5.
Sega et al., J. Natl. Cancer Inst. 61 (1980) 1001-6.
Marmor et al., Cancer, 43 (1979) 188-97.
Sugaar et al., Cancer 43 (1979) 767-83.
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