Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1995-06-05
1997-09-09
Elliott, George C.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
536 221, 536 231, 536 2431, 536 2432, 536 2433, 435 6, 435912, 4353201, 435325, C07H 2102, C07H 2104, C12P 1934, C12Q 168
Patent
active
056658745
ABSTRACT:
A method of determining the prognosis of a solid tumor is provided, in which a sample from a patient bearing a tumor is assayed for the presence of a protein which is immunologically cross-reactive with the hpr gene product, but not with haptoglobin 1 or haptoglobin 2. Also provided is a method for preparing antibodies specific for this diagnostic marker which correlates with early relapse and metastasis of breast and other cancers. The marker can be detected using immunological methods employing antibodies specific for Hpr protein and not cross-reactive with haptoglobins 1 or 2.
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Chalbos, et al., "
Kuhajda Francis P.
Pasternack Gary R.
Elliott George C.
Fredman Jeffrey
John Hopkins University
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