Optics: measuring and testing – By dispersed light spectroscopy – With sample excitation
Reexamination Certificate
2011-01-11
2011-01-11
Evans, F. L (Department: 2877)
Optics: measuring and testing
By dispersed light spectroscopy
With sample excitation
C356S039000, C356S318000, C250S459100
Reexamination Certificate
active
07869033
ABSTRACT:
The optical analysis of body fluids is a method of determining the relative concentration of certain bio-molecules in blood and urine samples by fluorescent spectroscopy. The relative concentration of these bio-molecules serves as a marker or screening test to assess the presence and stage of cancer in some organ or tissue of the body, and in some cases, the presence of particular types of cancer in the body. The bio-molecules include various species of porphyrin, flavins (including flavin mononucleotide[FMN], flavin adeno dinucleotide [FAD], and riboflavin), bile components (including biliverdin and bilirubin), tyrosine, tryptophan, and NAD(P)H. The fluorescent spectroscopy techniques include determining intensity maxima in the emission spectra at particular excitation wavelengths characteristic of the bio-molecules, determining intensity maxima in the excitation spectra at particular emission wavelengths characteristic of the bio-molecules, and synchronous scanning of the excitation and emission spectra while maintaining particular offsets in the wavelengths.
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Elangovan Masilamani
Masilamani Vadivel
Evans F. L
Litman Richard C.
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