Cancer control

Details Cancer control Cancer control

2006-07-04

2006-07-04

McGarry, Sean (Department: 1635)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S007100, C536S024310

Reexamination Certificate

active

07070931

ABSTRACT:
Clarification of the relationship between the functions of E1AF gene and the invasion and metastasis of cancers, and application thereof to cancer control, more specifically the control of cancer cell invasion by controlling the expression of E1AF gene and the products of expression, and the detection and diagnosis of cancers by detecting the products of expression of E1aF gene.

REFERENCES:
patent: 5552390 (1996-09-01), Scholar et al.
patent: 5744460 (1998-04-01), Muller et al.
patent: 5872242 (1999-02-01), Monia et al.
patent: 5874415 (1999-02-01), Kufe et al.
patent: 6566063 (2003-05-01), Kaufmann et al.
patent: 05-328975 (1993-12-01), None
patent: 94 02595 (1994-02-01), None
patent: 95 13380 (1995-05-01), None
patent: 96 18736 (1996-06-01), None
Noromi et al. Journal of Urology, vol. 157(4 Suppl):149, 1997.
Hida et al. American Journal of Pathology, vol. 150(6): 2125-2132, 1997.Hida et al. Proceedings of the American Association for Cancer Research Annual Meeting, vol. 37(0): 506, 1996.
Kaya et al. Oncogene, vol. 12: 221-227, 1996.
Taguchi et al. Jpn. J. Cancer Res., vol. 88: 394-400, 1997.
Branch, A., “A Good Antisense is Hard to Find,” TIBS vol. 23:45-50 (1998).
Stull et al., “Antigene, Ribozyme and Aptamer Nucleic Acid Drugs: Progress and Prospects,” Pharmaceutical Research vol. 12(4) 465-483 (1995).
Agrawal et al., “Antisence oligonucleiotides: Towards Clinical Trrials,” TIBTECH vol. 14:376-387 (1996).
Chemical Abstract, vol. 112 (1990), Abstract No. 93211.
Chemical Abstract, vol. 118 (1993), Abstract No. 75422.
F. Higashino et al., “Isolation of a cDNA encoding the adenovirus E1A enhancer binding protein: a new human member of the ets oncogene family,” Nucleic Acids Research, vol. 21, No. 3, pp. 547-553, 1993.
J. Xin et al., “Molecular cloning and characterization of PEA3, a new member of the Ets oncogene family that is differentially expressed in mouse embryonic cells,” Genes & Development, 6, pp. 481-496, 1992.
B. Wasylyk et al., “The Ets family of transcription factors,” European Journal of Biochemistry, 211, pp. 7-18, 1993.
M. Gaire et al., “Structure and Expression of the Human Gene for the Matrix Metalloproteinanse Matrilysin,” Journal of Bioogical Chemistry, vol. 269, No. 3, pp. 2032-2040, 1994.
P. Huhtala et al., “Complete Structure of the Human Gene for 92-kDA Type IV Collagenase,” Journal of Biological Chemistry, vol. 266, No. 25, pp. 16485-16490, 1991.
P. Huhtala et al., “Structure of the Human Type IV Collagenase Gene,” Journal of Biological Chemistry, vol. 265, No. 19, pp. 11077-11082, 1990.
M. Koizumi et al., “Construction of a series of several self-cleaving RNA duplexes using synthetic 21-mers,” Federation of European Biochemical Societies, vol. 228, No. 2, pp. 228-230, 1988.
P. Angel et al., “12-O-Tetradecanoyl-Phorbol-13-Acetate Induction of the Human Collagenase Gene is Mediated by an Inducible Enhancer Element Located in the 5′-Flanking Region,” Molecular Cellular Biology, vol. 7, No. 6, pp. 2256-2266, 1987.
S. Whitham et al., “Comparison of human stromelysin and collegenese by cloning and sequence analysis,” Biochemical Journal, vol. 240, pp. 913-916, 1986.
D. Muller et al., “The collagenase gene family in humans consists of at least four members,” Biochemical Journal, vol. 253, pp. 187-192, 1988.
L. Laimins, et al., “Characterization of Enhancer Elements in the Long Terminal Repeat of Moloney Murine Sarcoma Virus,” Journal of Virology, vol. 49, No. 1, pp. 183-189, 1984.
K. Sirum et al., “Cloning of the Genes for Human Stromelysin and Stromelysin 2: Differential Expression in Rheumatoid Synovial Fibroblasts,” Biochemistry, vol. 28, No. 22, pp. 8691-8698, 1989.
C. Gorman et al., “Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells,” Molecular and Cellular Biology, vol. 2, No. 9, pp. 1044-1051 (1982).
Y. Severne et al., “Metal binding ‘finger’ structure in the glucocorticoid receptor defined by site-directed mutagnesis,” The EMBO Journal vol. 7, No. 8, pp. 2503-2508, 1988.
P. Matthias et al., “Eukaryotic expression vectors for the analysis of mutant proteins,” Nucleic Acids Research, vol. 17, No. 5, p. 6418, 1989.
C. Gorman et al., “The Rous earcoma virus long terminal repeat is a strong promoter when introduced into a variety of eukaryotic cells by DNA-mediated transfection,” Proceedings of the National Academy of Sciences of the United States of America, vol. 79, pp. 6777-6781 1982.
P. Southern et al., “Transformation of Mammalian Cells to Antibiotic Resistance with a Bacterial Gene Under Control of the SV4O Early Region Promoter,” Journal of Molecular and Applied Genetics, vol. 1, No. 4, pp. 327-341 1982.
A. Albini et al., “A Rapid in Vitro Assay for Quantitating the Invasive Potential of Tumor Cells,” Cancer Research, vol. 47, pp. 3239-3424, 1987.
Y. Kuwano et al., “The Primary Structure of Rat Ribosomal Protein L38,” Biochemical and Biophysical Research Communications, vol. 175, No. 2, pp. 551-555, 1991.
A. Ricco et al., “The Human urokinase-plasminogen activator gene and its promoter,” Nucleic Acids Research, vol. 13, No. 8, pp. 2759-2771, 1985.
J. Tso et al., “Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene,” Nucleic Acids Research, vol. 13, No. 7, pp. 2485-2502, 1985.
K. Yoshida et al., “Binding sites of HeLa cell nuclear proteins on the upstream region of adenovirus type 5 E1A gene,” Nucleic Acids Research, vol. 17, No. 23, pp. 10015-10034, 1989.
Abstract-XP002142893, “Role of matrix metalloproteinase in invasion ans metastasis: Biology, diagnosis and inhibitors,” Bioscience Information Services, Philadelphia, PA; 12(1-3):367-384 (1993).
Wang, et al., “Matrix Metalloproteinase Inhibitor BB-94 (Batimastat) Inhibits Human Colon Tumor Growth and Spread in a Patient-like Orthotopic Model in Nude Mice,” Cancer Research; 54:4726-4728 (1994).
Higashino, et al., “Ets-related protein E1A-F can activate three different matrix metalloproteinase gene promoters,” Oncogene; 10:1461-1463 (1995).
Higashion, et al., “Isolation of a cDNA encoding the adenovirus E1A enhancer binding protein: a new human member of theetsoncogene family,” Nucleic Acids Research, 21(3):547-553 (1993).
Smolle, et al., “Tumor-cell Motility and Invasion within Tumors Determined by Applying Computer Simulation to Histologic Patterns,” Int. J. Cancer; 50:331-335 (1992).
Shapiro, et al., “Antisense-mediated Reduction in Insulin-like Growth Factor-I Receptor Expression Suppresses the Malignant Phenotype of a Human Alveolar Rhabdomyosarcoma,” J. Clin. Invest.; 94:1235-1242 (1994).
Lester, et al., “Tumor Cell Adhesion to the Extracellular Matrix and Signal Transduction Mechanisms Implicated in Tumor Cell Motility, Invasion and Metastasis,” Cancer and Metastasis Reviews; 11:31-44 (1992).
Hofmann-Wellenhof, et al., “Correlation of Melanoma Cell Motility and Invasionin vitro,” Melanoma Research; 5:311-319 (1995).
Tenth International Conference on AIDS International Conference on STD-Abstract Book vol. II Yokohama, Japan Aug. 7-12, 1994.
Yung, et al., “New Approaches to Molecular Therapy of Brain Tumors,” Current Opinion in Neurology; 7:501-505 (1994).
Kook, et al., “The Effect of Antisense Inhibition of Urokinase Receptor in Human Squamous Cell Carcinoma on Malignancy,” The EMBO Journal 13(17): 3983-3991 (1994).
Abstract of Hutcherson, et al., “Antisense Oligonucleotide Safety and Efficacy for CMV Retinitis in AIDS Patients”.
Yamanaka, et al., “Growth Inhibition of Human Glioma Cells Modulated by Retrovirus Gene Transfection wit

Affiliated with

Also associated with

Rating

Cancer control does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Cancer control, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cancer control will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3586149