Cancer associated protein

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues

Reexamination Certificate

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Details

C530S350000, C530S326000, C530S328000, C436S064000, C436S086000

Reexamination Certificate

active

10736227

ABSTRACT:
The present invention relates to a novel polypeptide (BCMP 101) compositions comprising the polypeptide, including vaccines, and antibodies that are immunospecific for the polypeptide. The use of the polypeptide in the diagnosis, prophylaxis and treatment of cancer, in particular breast cancer is also provided.

REFERENCES:
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patent: 2003/0092898 (2003-05-01), Salceda et al.
patent: WO 00/55628 (2000-09-01), None
patent: WO 01/13117 (2001-02-01), None
patent: WO 01/13117 (2001-02-01), None
patent: WO 02/64611 (2002-08-01), None
Amino acid databases, GenCore. Sequence alignment between US 2003/0092898 A1 sequence 267 and Applicants' SEQ ID No: 1, May 15, 2003.
Amino acid databases, GenCore. Sequence alignment between US Patent 5,776,687 sequence 12 and Applicants' SEQ ID No: 1, Jul. 7, 1998.
Baselga, J., et al., Recombinant Humanized Anti-HER2 Antibody(Herceptin™)Enhances the Antitumor Activity of Paclitaxel and Doxorubicin against HER2
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ABSTRACT for Craggs, et al., 2003, Applied Genomics & Proteomics 2(2):101-100.
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Lucas S., et al., MAGE-5B, MAGE-B6, MAGE-C2, and MAGE-C3: Four New Members Of The MAGE Family With Tumor-Specific Expression, 2000, Int.J. Cancer 87:55-60.
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Saffran, D.C., et al., Targget antigens for prostate cancer immunotherapy, 1999, Cancer Metastasis Rev. 18: 437-449.
Shiku, H., et al.,Development of a cancer vaccine: peptides, proteins, and DNA 2000, Cancer Chemother. Pharmacol. 46:S77-82.
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Vermeulen, S.J., et al., The αE-catenin gene (CTNNA1) acts as an invasion-suppressor gene in human colon cancer cells, 1999, Oncogene 18: 905-915.
Database EMBL online Dec. 1, 2001 “NSE2 Protein” Database Accession No. Q96Kn1 XP002234948.

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