Cancer-associated antigen

Details Cancer-associated antigen Cancer-associated antigen

2011-06-07

2011-06-07

Rawlings, Stephen L (Department: 1643)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Nucleoproteins, e.g., chromatin, chromosomal proteins,...

C530S350000

Reexamination Certificate

active

07956162

ABSTRACT:
The present invention provides a novel cancer-associated antigen that can be used in the treatment and diagnosis of cancer. Further, the invention provides amino acid and nucleic acid sequence of the novel antigen, binding proteins, and immuno-conjugates. The invention also relates to diagnostic and therapeutic methods and kits.

REFERENCES:
patent: 2008/0213922 (2008-09-01), Chahal
patent: WO 2006/105653 (2006-10-01), None
De Craene, B. et al. “Unravelling signalling cascades for the Snail family of transcription factors”, Cellular Signalling, 2005, vol. 17, No. 5, p. 535-547.
Nakaura, E.K. et al. “Mammalian Scratch: A neural-specific Snail family transcriptional repressor”, Proceedings of the Nat. Academy of Sc. USA, 2001, vol. 98, p. 4010-4015.
Nieto, M.A. “The snail superfamily of zine-finger transcription factors” Nature Reviews Mol. Cell Biol., 2002, vol. 3, No. 3, p. 155-166.
Roark, M. et al. “Scratch, a pan-neural gene encoding a zinc finger protein related to snail, promotes neural development”, Genes & Develop., 1995, vol. 9, No. 19, p. 2384-2398.

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