Chemistry: molecular biology and microbiology – Vector – per se
Patent
1997-01-16
1999-03-30
Caputa, Anthony C.
Chemistry: molecular biology and microbiology
Vector, per se
435325, 435693, 536 237, C12N 1531
Patent
active
058888101
ABSTRACT:
A fusion protein which comprises the B subunit of the labile toxin (LT-B) of E. coli and part of the flagellin (flaA) protein of C. jejuni is antigenic and is useful for decreasing colonization in chickens by Campylobacter species. The protein is produced by E. coli cells, transformed by the plasmid pBEB into which DNA sequences encoding the novel protein have been introduced.
REFERENCES:
Khoury,C.A. "Isolation, Characterization, Sequencing, and Expression of the Campylobacter jejeniflagellar gene and assessment of the Expressed flagellar protein as a chicken vaccine". Ph.D. Thesis Athens, Georgia University of Georgia 1992.
Helmann, J.D., Molec. Microbiol., vol. 5, pp. 2875-2882 (1991).
Khawaja et al, Curr. Microbiol., vol. 24, pp. 213-221 (1992).
Fisher et al., Molec. Microbiol.,vol. 5, pp. 1151-1158 (1991).
Nuitjen et al., J. Biochem. Chem., vol. 265, pp. 17798-17804 (1990).
Wang et al., J. Bacteriol., vol. 172, pp. 949-955 (1990).
Labigne-Roussel et al., J. Bacteriol., vol. 169, pp. 5320-5323 (1987).
Labigne-Roussel et al., J. Bacteriol., vol. 170, pp. 1704-1708 (1988).
Clements, J.D., Infect. Immun., vol. 58, pp. 1159-1166 (1990).
Jagusztyn-Krynicka et al., Infec. Immun., vol 61, pp. 1004-1015 (1993).
Nakayama et al., Biotechnology, vol. 6, pp. 693-697 (1988).
Khoury Christian A.
Meinersmann Richard J.
Caputa Anthony C.
Fado John
Graeter Janelle S.
Silverstein M. Howard
The United States of America as represented by the Secretary of
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