Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Chemical modification or the reaction product thereof – e.g.,...
Patent
1997-03-31
1998-11-17
Caputa, Anthony C.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Chemical modification or the reaction product thereof, e.g.,...
530402, 530825, 4241901, 4241921, 4241931, 4241941, 42419711, 4242411, 4242421, C07K 14205, C07K 14245
Patent
active
058378251
ABSTRACT:
A fusion protein which comprises the B subunit of the labile toxin (LT-B) of E. coli and part of the flagellin (flaA) protein of C. jejuni is antigenic and is useful for decreasing colonization in chickens by Campylobacter species. The protein is produced by E. coli cells, transformed by the plasmid pBEB into which DNA sequences encoding the novel protein have been introduced.
REFERENCES:
patent: 4411888 (1983-10-01), Klipstein et al.
McSweegan et al. Intection and Immunity 53(1):141-148 1986.
Logan et al. Journal of Bacteriology 168(2):739-745 1986.
Khoury et al. Disserstation Abstracts 54(2B):646 Aug. 1993.
Helmann, J.D., Molec. Microbiol., vol. 5, pp. 2875-2882 (1991).
Khawaja et al., Curr. Microbiol., vol. 24, pp. 213-221 (1992).
Fisher et al., Molec. Microbiol., vol. 5, pp. 1151-1158 (1991).
Nuitjen et al., J. Biochem. Chem., vol. 265, pp. 17798-17804 (1990).
Wang et al., J. Bacteriol., vol. 172, pp. 949-955 (1990).
Labigne-Roussel et al., J. Bacteriol., vol. 169, pp. 5320-5323 (1987).
Labigne-Roussel et al., J. Bacteriol., vol. 170, pp. 1704-1708 (1988).
Clements, J.D., Infect. Immun., vol. 58, pp. 1159-1166 (1990).
Jagusztyn-Krynicka et al., Infec. Immun., vol. 61, pp. 1004-1015 (1993).
Nakayama et al., Biotechnology, vol. 6, pp. 693-697 (1988).
Khoury Christian A.
Meinersmann Richard J.
Caputa Anthony C.
Fado John
Graeter Janelle S.
Silverstein M. Howard
The United States of America as represented by the Secretary of
LandOfFree
Campylobacter jejuni flagellin/Escherichia coli LT-B fusion prot does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Campylobacter jejuni flagellin/Escherichia coli LT-B fusion prot, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Campylobacter jejuni flagellin/Escherichia coli LT-B fusion prot will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-885492