Campylobacter jejuni antigens and methods for their production a

Details Campylobacter jejuni antigens and methods for their production a Campylobacter jejuni antigens and methods for their production a

1995-03-13

1999-02-23

Caputa, Anthony C.

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

435348, 435362, 435365, 435367, 4352523, 43525233, 43525231, 4352542, 43525421, 4353201, 435 693, 536 237, C12N 1531, C12N 1563, C12N 1570, C12N 1579

Patent

active

058743006

ABSTRACT:
The present invention provides an isolated nucleic acid encoding an approximately 26 kilodalton antigen, PEB1A, of Campylobacter jejuni, or an antigenic fragment thereof, wherein the antigen is associated with diarrheal disease. The present invention also provides methods of detecting the presence of a Campylobacter jejuni strain possessing the PEB1A antigen in a subject. Vaccines and treatments for C. jejuni infection are provided, as is a mutant C. jejuni not expressing a functional PEB1A antigen.

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