Camptothecin derivatives having antitumor activity

Details Camptothecin derivatives having antitumor activity Camptothecin derivatives having antitumor activity

2006-09-12

2006-09-12

Maier, Leigh C. (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C514S033000, C514S280000, C514S283000, C536S004100, C536S017200, C536S018700, C546S048000

Reexamination Certificate

active

07105492

ABSTRACT:
Camptothecin derivatives of camptothecin of formula (I)exhibit antitumor activity and show a good therapeutic index and are used in the treatment of tumors, viral infections and antiplasmodium falciparum.

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CAS abstract of WO 98/07727.
Wang, H.-K. et al “Novel water-soluble 7-acylhydrazono-(formyl camptothecins . . . ” Bioorg. & Med Chem. Lett. vol. 4, No. 4, pp. 579-582 1994.

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