Camptothecin analogues

Details Camptothecin analogues Camptothecin analogues

1976-01-05

1977-06-21

Daus, Donald G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424258, C07D49122

Patent

active

040310981

ABSTRACT:
Camptothecin analogues showing more potent anti-tumor activity than a naturally occurring alkaloid camptothecin, which also exhibit an immunosuppressive activity, in which the 1-ethyl of camptothecin is replaced by various members of substitutents such as alkyls (except ethyl), alkenyls, alkynyls, aralkyls or aryloylalkyls; being produced from readily accessible starting materials on totally synthetic method newly developed by the present inventor.

REFERENCES:
patent: 3894029 (1975-07-01), Winterfeldt et al.

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