Calibrator and use thereof in an immunoassay

Chemistry: analytical and immunological testing – Composition for standardization – calibration – simulation,... – Blood serum or blood plasma standard or control

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436 15, 435 794, 435 13, 435963, 435967, 530382, 530856, G01N 3396, G01N 3368, G01N 3353

Patent

active

057598584

ABSTRACT:
The invention relates to a composition comprising among others a fibrinopeptide A releasing compound. Furthermore the invention relates to the use of the composition as calibrator in plasma containing fibrinogen. A test kit comprising the said composition and a method to determine soluble fibrin also belong to the invention.

REFERENCES:
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patent: 4692406 (1987-09-01), Becker et al.
patent: 5099004 (1992-03-01), Nieuwenhuizen
patent: 5116950 (1992-05-01), Miyano et al.
patent: 5188940 (1993-02-01), Krause et al.
Scheefers-Borchel et al, 1985. Discrimination Between Fibrium and Fibrinogen by a Monoclonal Antibody Against a Synthetic Peptide. Proc. Natl. Acad. Sci. 82:7091-5.
Brosstad et al, 1977. Same Characteristics of Various Fibrium Monomer Preparations Made from Dissolved Fibrium Clots. Haemostasis 6:213-24.

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