Calibration technique for non-invasive medical devices

Details Calibration technique for non-invasive medical devices Calibration technique for non-invasive medical devices

2005-03-08

2005-03-08

Winakur, Eric F. (Department: 3736)

Surgery

Diagnostic testing

Measuring or detecting nonradioactive constituent of body...

C600S317000, C600S322000

Reexamination Certificate

active

06865407

ABSTRACT:
There is a need for a non-invasive method of calibrating medical devices at the point of care, where the calibration is performed without the removal of blood or bodily fluids. The invention is directed to an approach for calibrating a first non-invasive sensor in which the tissue being measured is modulated in some way so as to after the value of the parameter being measured by the first optical sensor. A second sensor detects another parameter that also changes with the modulation. The second sensor is absolutely calibrated. Where there is a known relationship between the first and second parameters, a calibration may be derived for the first sensor. Such a technique is applicable to calibrating non-invasive sensors for monitoring a wide variety of physiologic parameters including, inter alia, glucose, blood gases, blood electrolytes and blood pH.

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