Calibration solutions useful for analyses of biological fluids a

Details Calibration solutions useful for analyses of biological fluids a Calibration solutions useful for analyses of biological fluids a

1992-08-28

1994-07-19

Niebling, John

Chemistry: electrical and wave energy

Apparatus

Electrolytic

204403, 204412, 204416, 204419, 20415312, 204433, 128635, 128760, G01N 2726

Patent

active

053306341

ABSTRACT:
Novel calibration solutions are provided which are useful, for example, with sensor assemblies used for analysis of CO.sub.2, especially in combination infusion fluid delivery/blood chemistry analysis systems which include a sensor assembly with each of the assembly electrodes mounted in an electrode cavity in the assembly. The analysis system used in the practice of the present invention typically includes provision for delivering infusion fluid and measuring blood chemistry during reinfusion of the physiological fluid at approximately the same flow rates. The invention calibration solutions are useful for calibrating an array of sensors capable of simultaneously measuring a number of blood chemistry parameters, including the partial pressures (tensions) of carbon dioxide and oxygen, pH (hydrogen ion), sodium, potassium, ionized calcium, ionized magnesium, chloride, glucose, lactate and hematocrit, in body fluids. More particularly, this invention relates to the use of an infusible intravenous solution to facilitate calibration on a regular basis for every individual sensor in a sensor assembly, which is in constant fluid communication with the body regardless of whether the sensors are ex vivo or in vivo.

REFERENCES:
patent: 5256660 (1993-10-01), Swan
Wilson, G. S., Topley and Wilsons Principles of Bacteriology and Immunity, 1955, p. 140.

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