Calibration of segmental blood volume changes in arteries and ve

Surgery – Truss – Pad

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A61B 502

Patent

active

057158282

ABSTRACT:
The method of calibrating the volume plethysmograph designed to detect atherosclerosis includes selecting discrete levels of cuff pressure and placing the artery under study at those discrete levels of induced pressure with a closed pneumatic cuff system, substantially continually sensing cuff pressures at each discrete level and thereby sensing blood volume change through the artery, electronically determining when a certain number of representative blood volume change signals are substantially equivalent, changing the volume in the closed pneumatic system at each discrete cuff pressure by a predetermined volumetric amount after determining substantial equivalency, electronically generating a calibration signal or factor at each discrete cuff pressure based upon changed blood volume change signal and, correcting the blood volume change representative signal based upon the calibration signal or factor at each discrete level of pressure. The calibration device includes, in one embodiment, a controllable pneumatic pump, a pressure sensor, a computerized device for determining when a representative number of blood volume change signals (based on the pressure sensor signals) are substantially similar and thereafter generating a calibration trigger signal. The calibration system also includes a device which changes the volume in the closed pneumatic system by a predetermined calibrated amount in the presence of the calibration trigger signal. This volume changing device may be a series of valves coupled by a chamber having a known volumetric size, a positive displacement pump driven by a stepper motor or a reciprocating piston.

REFERENCES:
patent: 4144878 (1979-03-01), Wheeler
patent: 4432374 (1984-02-01), Osanai
patent: 5241963 (1993-09-01), Shankar
patent: 5297556 (1994-03-01), Shankar
patent: 5566677 (1996-10-01), Raines et al.

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