Calibration device for heterogeneous immunoassay

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435 4, 435188, 435805, 435810, G01N 33577, G01N 33545

Patent

active

047910569

ABSTRACT:
A device is disclosed for use in a simultaneous calibration assay method wherein a conjugate of a catalyst and a member of a specific binding pair ("mip") is employed. The present device comprises a surface to which a receptor is non-diffusively bound. The receptor is capable of specific binding to the conjugate of the catalyst and mip and is substantially incapable of binding to the catalyst or the mip apart from the conjugate. The surface may be an integral part of, or separate from, a support.

REFERENCES:
patent: 4230683 (1980-10-01), Decker et al.
patent: 4366241 (1982-12-01), Tom et al.
patent: 4533629 (1985-08-01), Litman et al.
patent: 4540659 (1985-09-01), Litman et al.
Litman et al., Clin. Chem., 29(1983), 1598-1603.

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