Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1995-06-07
1997-11-18
Walsh, Stephen
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
435 691, 435 71, 4352901, 4352523, 4353201, 530300, 530350, 530324, 530326, 536 231, 536 2431, C07K 4705, C12N 1512
Patent
active
056889380
ABSTRACT:
The present invention relates to the different roles inorganic ion receptors have in cellular and body processes. The present invention features: (1) molecules which can modulate one or more inorganic ion receptor activities, preferably the molecule can mimic or block an effect of an extracellular ion on a cell having an inorganic ion receptor, more preferably the extracellular ion is Ca.sup.2+ and the effect is on a cell having a calcium receptor; (2) inorganic ion receptor proteins and fragments thereof, preferably calcium receptor proteins and fragments thereof; (3) nucleic acids encoding inorganic ion receptor proteins and fragments thereof, preferably calcium receptor proteins and fragments thereof; (4) antibodies and fragments thereof, targeted to inorganic ion receptor proteins, preferably calcium receptor protein; and (5) uses of such molecules, proteins, nucleic acids and antibodies.
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Brown Edward M.
Fuller Forrest H.
Garrett, Jr. James E.
Hebert Steven C.
NPS Pharmaceuticals Inc.
Sorensen Kenneth A.
The Brigham & Women's Hospital, Inc.
Walsh Stephen
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