Drug – bio-affecting and body treating compositions – Inorganic active ingredient containing – Phosphorus or phosphorus compound
Reexamination Certificate
2007-12-17
2009-11-24
Henley, III, Raymond J (Department: 1614)
Drug, bio-affecting and body treating compositions
Inorganic active ingredient containing
Phosphorus or phosphorus compound
C424S717000
Reexamination Certificate
active
07622139
ABSTRACT:
A composition for delivery of osteogenic proteins is disclosed. The composition comprises an osteogenic protein, a calcium phosphate material as a carrier, and an effective amount of an effervescent agent. Methods of making the compositions and methods of using the osteogenic compositions to treat osteoporotic and/or osteopenic bone are also disclosed.
REFERENCES:
patent: 2465357 (1949-03-01), Correll et al.
patent: 3955719 (1976-05-01), Pheulpin
patent: 4159358 (1979-06-01), Hench et al.
patent: 4191747 (1980-03-01), Scheicher
patent: 4563489 (1986-01-01), Urist
patent: 4596574 (1986-06-01), Urist
patent: 4758233 (1988-07-01), Phillips et al.
patent: 4784055 (1988-11-01), Langen et al.
patent: 4851521 (1989-07-01), della Valle et al.
patent: 5013649 (1991-05-01), Wang et al.
patent: 5024841 (1991-06-01), Chu et al.
patent: 5118667 (1992-06-01), Adams et al.
patent: 5124316 (1992-06-01), Antoniades et al.
patent: 5171579 (1992-12-01), Ron et al.
patent: 5256418 (1993-10-01), Kemp et al.
patent: 5308889 (1994-05-01), Rhee et al.
patent: 5324519 (1994-06-01), Dunn et al.
patent: 5324775 (1994-06-01), Rhee et al.
patent: 5328955 (1994-07-01), Rhee et al.
patent: 5352715 (1994-10-01), Wallace et al.
patent: 5356629 (1994-10-01), Sander et al.
patent: 5422340 (1995-06-01), Ammann et al.
patent: 5447725 (1995-09-01), Damani et al.
patent: 5464440 (1995-11-01), Johansson
patent: 5492697 (1996-02-01), Boyan et al.
patent: 5520923 (1996-05-01), Tjia et al.
patent: 5645592 (1997-07-01), Nicolais et al.
patent: 5650176 (1997-07-01), Lee et al.
patent: 5674292 (1997-10-01), Tucker et al.
patent: 5676976 (1997-10-01), Lee et al.
patent: 5752974 (1998-05-01), Rhee et al.
patent: 5789543 (1998-08-01), Ingham et al.
patent: 5935594 (1999-08-01), Ringeisen et al.
patent: 5939323 (1999-08-01), Valentini et al.
patent: 5972368 (1999-10-01), McKay
patent: 6077076 (2000-06-01), Comfort
patent: 6699471 (2004-03-01), Radice et al.
patent: 7413753 (2008-08-01), Li et al.
patent: 2002/0187104 (2002-12-01), Li et al.
patent: 2002/0193883 (2002-12-01), Wironen
patent: 0 058 481 (1982-08-01), None
patent: 0 329 239 (1989-08-01), None
patent: 0 530 804 (1993-03-01), None
patent: 07-0246235 (1995-09-01), None
patent: 11511722 (1999-10-01), None
patent: WO 91/17777 (1991-11-01), None
patent: WO 92/05199 (1992-04-01), None
patent: WO 93/00050 (1993-01-01), None
patent: WO 93/06872 (1993-04-01), None
patent: WO 93/20858 (1993-10-01), None
patent: WO 96/36562 (1996-11-01), None
patent: WO 96/39203 (1996-12-01), None
patent: WO 96/40297 (1996-12-01), None
patent: WO 97/45532 (1997-12-01), None
patent: WO 97/49412 (1997-12-01), None
patent: WO 98/31788 (1998-07-01), None
patent: WO 98/40113 (1998-09-01), None
patent: WO 99/24070 (1999-05-01), None
patent: WO 99/38543 (1999-08-01), None
patent: WO 00/37124 (2000-06-01), None
patent: WO 01/28602 (2001-04-01), None
patent: WO 01/28603 (2001-04-01), None
patent: WO 02/058755 (2002-08-01), None
patent: WO 02/100331 (2002-12-01), None
patent: WO 03/099992 (2003-12-01), None
Fleisch, Bisphosphonates in bone disease, From the Laboratory to the patient, 3rd Ed. Parthenon Publishing (1997).
International Preliminary Examination Report for PCT/US02/17798.
International Search Report for PCT/US02/17798.
Lee et al., Clin. Orthoped. Rel. Res., 367S:S396-S405 (1999).
Stedman's Medical Dictionary, 25th Ed. p. 38 “air” (1990).
Urist et al., Clin. Orthoped. Rel. Res., 214:295-304 (1986).
Urist et al., Clin. Orthoped. Related Res., 187:277-280 (1984).
Campoccia et al., “Semisynthetic Resorbabel Materials From Hyaluronan Esterification”,Biomaterials, 19:2101-27 (1998).
Gerhart et al., “Healing of Large Mid-Femoral Segmental Defects in Sheep Using Recombinant Human Bone Morphogenetic Protein (BMP-2”,Trans. Othop. Res. Soc., 16:172 (1991).
Leslie M., Nurse Practitioner, 24:38, 41-8 (1999).
Ohura et al., “Resporation of, and Bone Formation From New β-tricalcium Phosphate-Monocalcium Phosphate Cements”,J. Biomed. Mat. Res., 30:193-200 (1996).
Ohura et al., “Healing of Segmental Bone Defects in Rats Induced by a β-TCP-MCPM Cement Combined with rhBMP-2”,J. Biomed. Mat. Res., 44:168-175 (1999).
Tona et al., “Extracellular Matrix in Regenerating Rat sciatic Nerve: A Comparative Study on the Localization of Laminin, Hyaluronic Acie, and Chondroitin Sulfate Proteoglycans, Including Versican”,J. Histochem. Cytochem., 41:591-599 (1993).
Toriumi et al., “Mandibular Reconstruction With a Recombinant Bone-Inducing Factor”,Arch. Otolatyngol. Head Neck Surg., 117:1101-1112 (1991).
Urist et al., “Bone Morphogenesis in Implants of Insoluble Bone Gelatin”,PNAS, 70:3511 (1973).
Wang, E.E., “Bone Morphognetic Protein-2 Causes Commitment and Differentiation in C3H10T1/2 and 3T3 Cells”,Trends in Biotech., 11:379-383 (1993).
Li Rebecca
Seeherman Howard
Tofighi Aliassghar
ETEX Corporation
Finnegan Henderson Farabow Garrett & Dunner L.L.P.
Henley, III Raymond J
Wyeth
LandOfFree
Calcium phosphate delivery vehicles for osteoinductive proteins does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Calcium phosphate delivery vehicles for osteoinductive proteins, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Calcium phosphate delivery vehicles for osteoinductive proteins will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4080247