Calcium phosphate cements prepared from silicate solutions

Details Calcium phosphate cements prepared from silicate solutions Calcium phosphate cements prepared from silicate solutions

2004-04-02

2010-10-26

Wax, Robert A (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

C424S400000, C424S422000, C424S426000, C623S023620

Reexamination Certificate

active

07820191

ABSTRACT:
Methods are provide for producing flowable compositions, e.g. pastes, that set into calcium phosphate products. In the subject methods, dry reactants that include a calcium source and a phosphate source are combined with a solution of a soluble silicate, e.g. sodium silicate, and the combined liquids and solids are mixed to produce the flowable composition. Also provided are the compositions themselves as well as kits for preparing the same. The subject methods and compositions produced thereby find use in a variety of applications, including the repair of hard tissue defects, e.g. bone defects.

REFERENCES:
patent: 4160012 (1979-07-01), Ono et al.
patent: 4161511 (1979-07-01), Shiraki et al.
patent: 4165368 (1979-08-01), Gaffar
patent: 4429691 (1984-02-01), Niwa et al.
patent: 4497075 (1985-02-01), Niwa et al.
patent: 4735857 (1988-04-01), Tagai et al.
patent: 4990163 (1991-02-01), Ducheyne et al.
patent: 5049157 (1991-09-01), Mittelmeier et al.
patent: 5218035 (1993-06-01), Liu
patent: 5266534 (1993-11-01), Atsumi et al.
patent: 5281265 (1994-01-01), Liu
patent: 5427768 (1995-06-01), Tung
patent: 5460803 (1995-10-01), Tung
patent: 5525148 (1996-06-01), Chow et al.
patent: 5534244 (1996-07-01), Tung
patent: 5545254 (1996-08-01), Chow et al.
patent: 5580623 (1996-12-01), Fulmer et al.
patent: 5605713 (1997-02-01), Boltong
patent: 5626861 (1997-05-01), Laurencin et al.
patent: 5648097 (1997-07-01), Nuwayser
patent: 5660624 (1997-08-01), Dry
patent: 5665121 (1997-09-01), Gie et al.
patent: 5679294 (1997-10-01), Umezu et al.
patent: 5681872 (1997-10-01), Erbe
patent: 5691397 (1997-11-01), Glimcher et al.
patent: 5695729 (1997-12-01), Chow et al.
patent: 5697981 (1997-12-01), Ison et al.
patent: 5783248 (1998-07-01), Lin et al.
patent: 5814681 (1998-09-01), Hino et al.
patent: 5874109 (1999-02-01), Ducheyne et al.
patent: 5875799 (1999-03-01), Petrus
patent: 5891233 (1999-04-01), Salonen et al.
patent: 5900254 (1999-05-01), Constantz
patent: 5914356 (1999-06-01), Erbe
patent: 5952010 (1999-09-01), Constantz
patent: 5954867 (1999-09-01), Chow et al.
patent: 5962028 (1999-10-01), Constantz
patent: 5968253 (1999-10-01), Poser et al.
patent: 5976234 (1999-11-01), Chow et al.
patent: 5997624 (1999-12-01), Chow et al.
patent: 6000341 (1999-12-01), Tung
patent: 6005162 (1999-12-01), Constantz
patent: 6027742 (2000-02-01), Lee et al.
patent: 6139578 (2000-10-01), Lee et al.
patent: 6201039 (2001-03-01), Brown et al.
patent: 6312468 (2001-11-01), Best et al.
patent: 6323146 (2001-11-01), Pugh et al.
patent: 6375935 (2002-04-01), Constantz
patent: 6379453 (2002-04-01), Lin et al.
patent: 6398859 (2002-06-01), Dickens et al.
patent: 6451059 (2002-09-01), Janas et al.
patent: 6458423 (2002-10-01), Goodson
patent: 6461632 (2002-10-01), Gogolewski
patent: 6518212 (2003-02-01), Wagh et al.
patent: 6703038 (2004-03-01), Schaefer et al.
patent: 6719993 (2004-04-01), Constantz
patent: 7175858 (2007-02-01), Constantz et al.
patent: 7252833 (2007-08-01), Constantz et al.
patent: 7252841 (2007-08-01), Constantz et al.
patent: 2002/0155167 (2002-10-01), Lee et al.
patent: 2003/0199615 (2003-10-01), Chaput et al.
patent: 2004/0076685 (2004-04-01), Tas
patent: 2004/0250730 (2004-12-01), Delaney et al.
patent: 2005/0023171 (2005-02-01), Delaney et al.
patent: 2005/0257714 (2005-11-01), Constantz et al.
patent: 2005/0260279 (2005-11-01), Constantz et al.
patent: 2007/0189951 (2007-08-01), Constantz et al.
patent: 11106251 (1999-04-01), None
patent: WO 00/23123 (2000-04-01), None
patent: WO 0023123 (2000-04-01), None
Kadiyala S. et al. Culture-expanded, bone marrow-derived mesenchymal stem cells can regenerate a critical-sized segmental bone defect. Tissue Engineering 1997 3(2): 173-185.
Constantz et al. Science 1995 267:1796-1799.
Yuan et al. Biomaterials 2000 21:1283-1290—available online Apr. 13, 2000.
Frankenburg et al. Journal of Bone and Joint Surgery 1998 80A:1112-1124.
Flautre et al. Bone 1999 25:35S-39S.
Goodman et al. Clinical Orthopedics and Related Research 1998 348:42-50.
E. Fernandez Production and Characterization of new calcium phosphate none cements in the CaHPO4-a-Ca3(PO4)2System:pH, workability and setting time.

Affiliated with

Also associated with

Rating

Calcium phosphate cements prepared from silicate solutions does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Calcium phosphate cements prepared from silicate solutions, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Calcium phosphate cements prepared from silicate solutions will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4150817