Calcium phosphate cement composition and a method for the...

Details Calcium phosphate cement composition and a method for the... Calcium phosphate cement composition and a method for the...

2005-08-16

2005-08-16

Lorengo, J. A. (Department: 1755)

Compositions: coating or plastic

Coating or plastic compositions

Inorganic settable ingredient containing

C106S035000

Reexamination Certificate

active

06929692

ABSTRACT:
The invention describes a new calcium phosphate cement powder, whose composition can best be described over the Ca/P molar ratio range of 1.35 to 1.40, most preferably 1.39, and whose two components were prepared by wet chemical synthesis procedures. One component is chemically-synthesized, bi-phasic alpha-TCP (Ca3(PO4)2, 95 wt %)+HA (Ca10(PO4)6(OH)2, 5 wt %) powder, while the second component is again a chemically-synthesized, single-phase DCPD (CaHPO4·2H2O) powder. A setting solution (Na2HPO4·2H2O) is used to form a self-setting calcium phosphate cement from the powder mixture. This cement can be used as bone filler or bone substitute in applications, which require higher rates of resorption.

REFERENCES:
patent: 5605713 (1997-02-01), Boltong
patent: 6616742 (2003-09-01), Lin et al.
Huipin Yuan et al., “Tissue responses of calcium phosphate cement: a study in dogs”, ELSEVIER Biomaterials 21 (2000) pp. 1283-1290.

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