Drug – bio-affecting and body treating compositions – Inorganic active ingredient containing – Aluminum – calcium or magnesium element – or compound containing
Patent
1990-04-18
1992-02-18
Waddell, Frederick E.
Drug, bio-affecting and body treating compositions
Inorganic active ingredient containing
Aluminum, calcium or magnesium element, or compound containing
424687, 514557, 514563, A61K 3310, A61K 3119, A61K 31195
Patent
active
050892762
ABSTRACT:
A composite which is obtainable by mixing calcium pantothenate with a per se neutral or basic magnesium or calcium lactate or carbonate in the presence of water and/or a lower alcohol, and drying the resulting mixture, is stable with little decrease of the content of calcium pantothenate during storage.
When other drugs, which may cause changes as the result of combination with calcium pantothenate, are combined to produce various preparations, the composite is stable because they are hardly affected by other ingredients and hardly affect other ingredients; for example, in production of tablets, powders, granules, and capsules, complicated processes to separate from other ingredients are not required, and the excessive amount in anticipation of the loss along with time can be reduced markedly.
REFERENCES:
patent: 3092548 (1963-06-01), Worton
patent: 3247064 (1966-04-01), Maekawa et al.
Chemical Abstracts 87(6):44247 Georgescu et al. (1977).
Chemical Abstracts 88(2): 11930 Georgescu et al. (1978).
Chemical Abstracts 93(4): 31777 Intreprinderea de Medicamento "Biofarm" (1980).
Ono Yasuo
Sumimura Kunihiko
Yamashita Junzou
Henley, III. Raymond J.
Takeda Chemical Industries Ltd.
Waddell Frederick E.
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