Chemistry: molecular biology and microbiology – Spore forming or isolating process
Patent
1994-07-27
1995-11-14
Wax, Robert A.
Chemistry: molecular biology and microbiology
Spore forming or isolating process
4353201, 536 232, C07H 2104
Patent
active
054665957
ABSTRACT:
The invention provides a novel calcium-independent cytosolic phospholipase A.sub.2 /B enzyme, polynucleotides encoding such enzyme and methods for screening unknown compounds for anti-inflammatory activity mediated by the arachidonic acid cascade.
REFERENCES:
patent: 5279957 (1994-01-01), Gross
patent: 5322776 (1994-06-01), Knopf et al.
patent: 5328842 (1994-07-01), Chiou et al.
patent: 5354677 (1994-10-01), Knopf et al.
Clark, J. D. (1991) "A novel arachidonic acid-selective cytosolic PLA.sub.2 contains a Ca.sup.2+ -dependent translocation domain with homology to PKC and GAP" Cell 65:1043-1051.
Sharp, J. D. et al. (1991) "Molecular cloning and expression of human Ca.sup.2+ -sensitive cytosolic phospholipase A.sub.2 " J. Biol. Chem. 266(23):14850-14853.
Han, J. H. et al. (1987) "Isolation of full-length putative rat lysophospholipase cDNA using improved methods for mRNA isolation and cDNA cloning" Biochemistry 26:1617-1625.
Aarsman et al., J. Biol. Chem. 264:10008 (1989).
Ackermann et al., FASEB J. 7:1237 (1993).
Ackermann et al., J. Biol. Chem. 269:9227 (1994).
Angle et al., Biochim. et Biophys. Acta 962:234 (1988).
Cao et al., J. Biol. Chem. 262:16927 (1987).
Ford et al., J. Clin. Invest. 88:331 (1991).
Gassama-Diagne et al., J. Biol. Chem. 264:9470 (1989).
Gross, TCM 2:115 (1992).
Gross et al., Biochemistry 32:327 (1993).
Hazen et al., J. Biol. Chem. 268:9892 (1993).
Hazen et al., J. Biol. Chem. 265:10622 (1990).
Hazen et al., J. Biol. Chem. 266:14526 (1991).
Hazen et al., Meth. in Enzymol. 197:400 (1991).
Hazen et al., J. Clin. Invest. 91:2513 (1993).
Hazen et al., J. Biol. Chem. 266:7227 (1991).
Hazen et al., Circulation Research 70:486 (1992).
Hazen et al., J. Biol. Chem. 266;5629 (1991).
Hirashima et al., J. Neurochem. 59:708 (1992).
Kanda et al., Biochem. and Biophys Res. Comm. 163:42 (1989).
Kramer et al., J. Biol. Chem. 264:5768 (1989).
Lehman et al., J. Biol. Chem. 268:20713 (1993).
Loeb and Gross, J. Biol. Chem. 261:10467 (1986).
Leslie et al., Biochim. et Biophys Acta. 963:476 (1988).
Nijssen et al., Biochim. et Biophys Acta 876:611 (1986).
Pierik et al., Biochim. et Biophys Acta 962:345 (1988).
Ramanadham et al., Biochemistry 33:7442 (1994).
Ramanadham et al., Biochemistry 32:337 (1993).
Ross et al., Archives of Biochem. and Biophys. 238:247 (1985).
Seilhamer et al., J. Biol. Chem. 264:5335 (1989).
Ueda et al., Biochem. and Biophys. Res. Comm. 195:1272 (1993).
Ulevitch et al., J. Biol. Chem. 263:3079 (1988).
Wolf and Gross, J. Biol. Chem. 260:7295 (1985).
Yost et al., Biochem. International 24:199 (1981).
Zupan et al., J. Med. Chem. 36:95 (1993).
Zupan et al., J. Biol. Chem. 267:8707 (1992).
Zupan et al., FEBS 23427 (1991).
Jones Simon
Tang Jin
Brown Scott A.
DesRosier Thomas J.
Genetics Institute Inc.
Lau Kawai
McDaniels Patricia A.
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