Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1997-06-27
2000-01-11
Kemmerer, Elizabeth
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
536 235, 536 231, 536 2431, 435325, 4352551, 4353201, C12N 1512
Patent
active
060134747
ABSTRACT:
Calcium channel (alpha).sub.1 -subunit and (alpha).sub.2 -subunit-encoding DNA, and related compositions and methods, are provided.
REFERENCES:
patent: 4788135 (1988-11-01), Davis et al.
patent: 4906564 (1990-03-01), Lyon et al.
patent: 4912202 (1990-03-01), Campbell et al.
patent: 4950739 (1990-08-01), Cherksey et al.
patent: 4954436 (1990-09-01), Froehner et al.
patent: 5051403 (1991-09-01), Miljanich et al.
patent: 5189020 (1993-02-01), Miljanich et al.
patent: 5264371 (1993-11-01), Miljanich et al.
patent: 5386025 (1995-01-01), Jay et al.
patent: 5401629 (1995-03-01), Harpold et al.
patent: 5407820 (1995-04-01), Ellis et al.
patent: 5424218 (1995-06-01), Miljanich et al.
patent: 5429921 (1995-07-01), Harpold
patent: 5436128 (1995-07-01), Harpold et al.
patent: 5618720 (1997-04-01), Ellis et al.
patent: 5643750 (1997-07-01), Spreyer et al.
patent: 5686241 (1997-11-01), Ellis et al.
patent: 5710250 (1998-01-01), Ellis et al.
patent: 5792846 (1998-08-01), Harpold et al.
patent: 5846757 (1998-12-01), Harpold et al.
patent: 5851824 (1998-12-01), Harpold et al.
patent: 5874236 (1999-02-01), Harpold et al.
Claudio et al., Genetic reconstitution of functional acetylcholine receptor channels in mouse fibroblasts, Science 238: 1688-1694 (1987).
Claudio et al., Stable expression of transfected Torpedo acetylcholine receptor .alpha. subunits in mouse fibroblast L cells, Proc. Natl. Acad. Sci. 84: 5967-5971 (1987).
Cooper et al., Purification and characterization of the dihydropyridine-sensitive voltage-dependent calcium channel from cardiac tissue, J. Biol. Chem. 262(2): 509-512 (1987).
Curran et al., Barium Modulates c-fos Expression and post-translational modification, Proc. Natl. Acad. Sci. USA 83:8521-8524 (1986).
Curtis et al., Reconstitution of the voltage-sensitive calcium channel purified from skeletal muscle transverse tubules, Biochemistry 25:3077-3083 (1986).
Curtis et al., Purification of the calcium antagonist receptor of the voltage-sensitive calcium channel from skeletal muscle transverse tubules, Biochemistry 23(10): 2113-2118 (1984).
Dascal et al., Expression of modulation of voltage-gated calcium channels after RNA injection in Xenopus oocytes, Science 231: 1147-1150 (1986).
Elliot et al., Role of calcium channel subtypes in calcium transients in hippocampal CA3 neurons, J. Neurosci. 15(10):6433-6444 (1995).
Ellis et al., Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose, Cell 45:721-732 (1986).
Ellis et al., Sequence and expression of mRNAs encoding the .alpha..sub.1 and .alpha..sub.2 subunits of DHP-sensitive calcium channel, Science 241:1661-1664 (1988).
Faramisco et al., Optimal spatial requirements for the location of basic residues in peptide substrates for the cyclic AMP-dependent protein kinase, J. Biol. Chem. 225(9):4240-4245 (1980).
Fisch et al., c-fos sequences necessary for basal expression and induction by epidermal growth factor, 12-O-tetradecanoyl phorbol-13-acetate, and the calcium ionophore, Mol. Cell. Biol. 7:3490-3502 (1987).
Gielow et al., Resolution and pharmacological analysis of the voltage-dependent calcium channels of Drosophila larval muscles, J. Neurosci. 15(9):6085-6093 (1995).
Greenberg et al., Stimulation of neuronal acetylcholine receptors induces rapid gene transcription, Science 234:80-83 (1986).
Akong et al., High-throughput measurement of intracellular Ca.sup.2+ by fluorescence imaging of a 96-well microtiter plate, Soc. Neurosci. Abstr. 21 (1995).
Barhanin et al., The calcium channel antagonists receptor from rabbit skeletal muscle: reconstitution after purification and subunit characterization, Eur. J. Biochem. 164:525-531 (1987).
Bezprozvanny et al., Voltage-dependent blockade of diverse types of voltage-gated Ca.sup.2+ channels expressed in Xenopus ooxytes by the Ca.sup.2+ channel antagonist mibefradil (Ro40-5967), Mol. Pharmacol. 48:540-549 (1995).
Blackshear et al., Protein kinase C-dependent and -independent pathways of proto-oncogene induction in human astrocytoma cells, J. Biol. Chem. 262(16):7774-7781 (1987).
Borsotto et al., The 1,4-dihydropyridine receptor associated with the skeletal muscle voltage-dependent Ca.sup.2+ channel, J. Biol. Chem. 260(26): 14255-14263 (1985).
Boulter et al., Functional expression of two neuronal nicotinic acetylcholine receptors from cDNA clones identifies a gene family, Proc. Natl. Acad. Sci. USA 84:7763-7767 (1987).
Brust et al., Human neuronal voltage-dependent calcium channels: studies on subunit structure and role in channel assembly, Neuropharmacology 32(11):1089-1102 (1993).
Catterall et al., Molecular properties of dihydropyridine-sensitive calcium channels in skeletal muscle, J. Biol. Chem. 263:3535-3538 (1988).
Mes-Masson et al., Overlapping cDNA clones define the complete coding region for the P210.sup.c-abl gene product associated with chronic myelogenous leukemia cells containing the Philadelphia chromosome, Proc. Natl. Acad. Sci. USA 83: 9768-9772 (1986).
Sambrook et al., Molecular Cloning, A Laboratory Manual, 2nd ed., NY: Cold Spring Harbor Laboratory Press, 1989, pp. 9.47-9.57, 16.3.
Scharf, Cloning with PCR, in PCR Protocols A Guide To Methods and Applications, Innis, M.A., et al., eds., New York: Academic Press; Chapter 11, pp. 84-91 (1990).
Varaldi et al., Acceleration of activation and inactivation by the .beta. subunit of the skeletal muscle calcium channel, Nature 352: 159-162 (1991).
Castellano et al., Cloning and expression of a neuronal calcium channle .beta. subunit, J. Biol. Chem. 268: 12359-12366 (1993).
Castellano et al., Rattus novegicus cDNA sequence, complete 5' and 3' UTR's, GenBank database record, acc. No. LO2315 (1993).
Emori et al., Isolation and sequence analysis of cDNA clones for the small subunit of rabbit calcium-dependent protease, J. Biol. Chem. 261: 9472-9476 (1986).
Hackett et al., DNA sequence analysis reveals extensive homologies of regions preceding hsp70 and .alpha..beta. heat shock genes in Drosophila melanogaster, Proc. Natl. Acad. Sci. USA 78: 6196-6200 (1981).
Hullin et al., Calcium channel .beta. subunit heterogeneity: functional expression of cloned cDNA from heart, aorta and brain, EMBO J. 11(3): 885-890 (1992).
Kim et al. "IgG from patients with Lambert-Eaton blocks voltage-dependent calcium channels." Science. 239:405-408 (1988).
Roberts, et al. "Paraneoplastic Myasthenic Syndrome IgG inhibits Ca flux in a small cell carcinoma." Nature. 317:737-739 (1985).
Young RA, and Davis RW. "Efficient isolation of genes using antibody probes." Proc. Natl. Acad. Sci. U.S.A. 80(5):1194-1198 (1983).
Nikaido et al., Molecular cloning of cDNA encoding human interleukin-2 receptor, Nature 311:631-636 (1984).
Noda et al., Existence of distinct sodium channel messenger RNAs in rat brain, Nature 320:188-192 (1986).
Noda et al., Expression of functional sodium channels from cloned cDNA, Nature 322:826-828 (1986).
Peralta et al., Distinct primary structures, ligand-binding properties and tissue-specific expression of four human muscarinic acetylcholine receptors, EMBO J. 6(13):3923-3929 (1987).
Rock et al., Biophysical and pharmacological characterization of stably expressed class B and class E Ca.sup.2+ channels in HEK 293 cells, Soc. Neurosci. Abstr. 21:508.1 (1995).
Sakurai et al., Immunochemical identification and differential phosphorylation of alternatively spliced forms of the .alpha..sub.1A subunit of brain calcium channels, J. Biol. Chem. 270(36):21234-21242 (1995).
Schmid et al., Immunochemical analysis of subunit structure of 1,4-dihydropyridine receptors associated with voltage-dependent Ca.sup.2+ channels in skeletal, cardiac, and smooth muscles, Biochemistry 25: 3492-3495 (1986).
Seager et al., Ann. N.Y. Acad. Sci. 522:43-46 (1988).
Sharp et al., Identification and characterization of the dihydropyridine-binding subunit of the skeletal muscle dihydropyridine receptor, J. Biol. Chem. 62:12309-12315 (1987).
Sieber et al., The 165-KDa peptide of the purified skeletal muscle dihydropyridine receptor contains the known regulatory sites of the calcium channe
Brenner Robert
Ellis Steven Bradley
Harpold Michael Miller
Schwartz Arnold
Williams Mark E.
Kemmerer Elizabeth
Lazar-Wesley Eliane
Seidman Stephanie L.
SIBIA Neurosciences Inc.
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