Calcium channel blockers comprising two benzhydril moieties

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S254110, C514S255010

Reexamination Certificate

active

06949554

ABSTRACT:
Certain piperazine substituted compounds are described which are useful in altering calcium channel activity.

REFERENCES:
patent: 3288795 (1966-11-01), Irikura et al.
patent: 4188485 (1980-02-01), Kukla
patent: 4918073 (1990-04-01), Ruger et al.
patent: 5386025 (1995-01-01), Jay et al.
patent: 5428038 (1995-06-01), Chatterjee et al.
patent: 5623051 (1997-04-01), Catterall et al.
patent: 5646149 (1997-07-01), Hellberg et al.
patent: 5703071 (1997-12-01), Itoh et al.
patent: 5866574 (1999-02-01), Okamura et al.
patent: 6011035 (2000-01-01), Snutch et al.
patent: 6294533 (2001-09-01), Snutch et al.
patent: 6310059 (2001-10-01), Snutch
patent: 6387897 (2002-05-01), Snutch
patent: 6458781 (2002-10-01), Connor et al.
patent: 6492375 (2002-12-01), Snutch
patent: 2001/0029258 (2001-10-01), Snutch
patent: 2004/0034035 (2004-02-01), Snutch et al.
patent: 2335461 (1999-06-01), None
patent: 2394327 (2001-06-01), None
patent: 0 187 524 (1986-07-01), None
patent: 0 213 006 (1987-03-01), None
patent: 0 458 387 (1991-11-01), None
patent: 0 496 691 (1992-07-01), None
patent: 504 202 (1983-01-01), None
patent: 514 167 (1983-04-01), None
patent: 8 304 135 (1983-05-01), None
patent: 8 305 343 (1983-07-01), None
patent: 920 416 (1963-03-01), None
patent: 1 513 883 (1978-06-01), None
patent: WO 94/14786 (1994-07-01), None
patent: WO 99/15129 (1999-04-01), None
patent: WO 99/25686 (1999-05-01), None
patent: WO 00/01375 (2000-01-01), None
patent: WO 00/18402 (2000-04-01), None
patent: WO 00/37059 (2000-06-01), None
patent: WO 01/45709 (2001-06-01), None
patent: WO-01/49670 (2001-07-01), None
patent: WO-03/068759 (2003-08-01), None
Boger et al., Helvetica Chimica Acta (2000) 83(8):1825-1845.
International Search Report for PCT/CA2004/000539, mailed on Dec. 22, 2004, 9 pages.
International Search Report for PCT/CA2004/001629, mailed on Jan. 21, 2005, 6 pages.
Jamieson et al., Synlett (2000) 11:1603-1607.
Toldy et al., Acta Chimica Academiae Scientiarum Hungarica (1965) 44:301-325.
Webster et al., Journal of the Chemical Society (2001 14:1673-1695.
International Search Report for PCT/CA2004/000535, mailed on Jul. 1, 2004, 5 pages.
Invitation to Pay Additional Fees for PCT/CA2004/000539, mailed on Sep. 2, 2004, 6 pages.
Bourinet et al. (1999).Nature Neuro2:407-415.
Chiarini, A. et al. (1996).Bioorg&Med Chem4(10):1629-1635.
Cohan, S. et al. (1991).Anns NY Acad Sci635:397-399.
Cribbs et al. (1998).Circ Res83:103-109.
Database WPI Week 9711 Derwent Publications Ltd., London, GB; Abstract JP 09 003067, XP002133055 (Hisamitsu Pharm Co Ltd.) Jan. 7, 1997.
De Waard et al. (1997).Ion ChannelsNarahashi, T. ed. Plenum Press, NY 4:41-87.
Dhainaut et al. (1992).J Med Chem35:2481-2496.
Dooley (1999).Current Op CPNS Investig Drugs1(1):116-125.
Dunlap et al. (1995).Trends Neurosci18:89-98.
Estep, K. et al. (1995).J Med Chem38(14):2582-2595.
Galizzi et al. (1986).PNAS USA83: 7513-7517.
Glamkowski, E. et al. (1977).J Med Chem20(11):1485-1489.
Gould et al. (1983).PNAS USA80:5122-5125.
Grantham et al. (1994).Brit J Pharmacol111:438-488.
Ito et al. (1994).Eur J Pharmacol257:203-210.
King et al. (1989).J Biol Chem264:5633-5641.
Lee et al. (1999).J Neurosci19:1912-1921.
Lehmann et al. (1988).Archiv der Pharmazie321(11):807-812.
McCleskey et al. (1991).Curr Topics Membr39:295-326.
Miyano, S. et al. (1990).Chem Pharm Bull38(6):1570-1574.
Ohtaka, H. et al. (1987).Chem Pharm Bull35(8):3270-3275.
Ohtaka, H. et al. (1987).Chem Pharm Bull35(10):4117-4123.
Perez-Reyes et al. (1998).Nature391:896-900.
Prasad, R. et al. (1968).J Med Chem11(6):1144-1150.
Sather et al. (1993).Neuron11:291-303.
Stea et al. (1994).PNAS USA91:10576-10580.
Stea et al.Handbook of Receptors and Channels(North, R.A. ed. CRC Press 1995) 113-151.
Tytgat, J. et al. (1991).Brain Res549(1):112-117.
Uneyama, H. et al. (1998).Calcium Ion Modulators, Sel Pap Satell Symp 13-23.
Vadodaria, D. et al. (1969).J Med Chem12:860-865.
Zikolova, S. et al. (1972).Tr. Nauchnoizsled Khim-Farm Inst8:59-67.
Zikolova, S. et al. (1984).Tr. Nauchnoizsled Khim-Farm Inst14:23-28.

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