Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-06-07
1998-11-24
MacMillan, Keith D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514320, 514324, 514317, A61K 31445
Patent
active
058407472
ABSTRACT:
A method for antagonizing or blocking calcium channels in vascular tissue, comprising administering to an animal in need thereof a pharmaceutically-effective amount of a compound having the formula ##STR1## wherein R.sup.1 and R.sup.3 are independently hydrogen, C.sub.1 -C.sub.4 alkyl, --CO--(C.sub.1 -C.sub.6 alkyl), or --CH.sub.2 Ar, --CO--Ar, wherein Ar is phenyl or substituted phenyl;
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patent: 5447941 (1995-09-01), Zuckerman
Collins et al., "Cardiovascular Protection by Oestrogen--A Calcium Antagonist Effect?", Lancet, 341, 1264-65 (1993).
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(CA) 95-225,950: Zuckerman, "Use of 2-phenyl-benzothiophene Cmpds. Such as Raloxifene--for Inhibiting Pulmonary Hypertensive Disease" EP 659426 95/06128. Abstract Only.
Boone David E.
Eli Lilly and Company
MacMillan Keith D.
Strode Janelle D.
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