Calcium binding recombinant antibody against protein C

Details Calcium binding recombinant antibody against protein C Calcium binding recombinant antibody against protein C

2007-07-24

2007-07-24

Canella, Karen A. (Department: 1643)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

C435S070100, C435S071200, C424S133100, C424S141100, C530S387100, C530S387300, C530S388100

Reexamination Certificate

active

08259321

ABSTRACT:
A Ca2+dependent recombinant antibody that specifically binds to a specific twelve peptide sequence (E D Q V D P R L I D G K) in the activation region of the Protein C has been constructed. The antibody does not bind to Activated Protein C and can be used to inhibit activation of Protein C by thrombin-thrombomodulin, in purification of Protein C, and in treatment of tumors.

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